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Q热心内膜炎:一名伴有体重减轻和厌食且胃活检标本中有肉芽肿的患者的疑难诊断

Q Fever Endocarditis: A Challenging Diagnosis in a Patient Referring Weight Loss and Anorexia, and With Granulomas in Gastric Biopsy Specimens.

作者信息

Lago-Rodriguez Ana Elena, Fraile-Ribot Pablo Arturo, Amengual-Antich Isabel, Gual-Capllonch Francisco, Garcia-Gasalla Mercedes

机构信息

Cardiology Department Hospital Universitario Son Espases Palma Illes Balears Spain.

Microbiology Department Health Research Institute of the Balearic Islands (IdISBa), Hospital Universitario Son Espases Palma Illes Balears Spain.

出版信息

Clin Case Rep. 2024 Nov 29;12(12):e9635. doi: 10.1002/ccr3.9635. eCollection 2024 Dec.

Abstract

Diagnosis of Q fever endocarditis is challenging since clinical findings are non-specific and diagnosis is mainly made by indirect methods such as serology. A progressive constitutional syndrome, severe asthenia, anorexia with no fever and histopathological findings of non-necrotizing gastric granulomas in a gastric biopsy were found preceding a cardiac failure in our case report. Prolonged treatment with doxycycline and hydroxychloroquine is mandatory, and cardiac valve surgery may be needed.

摘要

Q热心内膜炎的诊断具有挑战性,因为临床表现不具特异性,诊断主要通过血清学等间接方法进行。在我们的病例报告中,在出现心力衰竭之前,发现了一种进行性全身性综合征、严重乏力、无发热的厌食症以及胃活检中非坏死性胃肉芽肿的组织病理学表现。强力霉素和羟氯喹的长期治疗是必需的,可能还需要进行心脏瓣膜手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1170/11606930/b92b990ab6d0/CCR3-12-e9635-g002.jpg

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