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[创伤后迟发性脊髓空洞症综合征。关于3例病例的发病机制理论]

[Late posttraumatic syringomyelic syndromes. Pathogenetic theories apropos of 3 cases].

作者信息

Leys D, Petit H, Lesoin F, Combelles G, Jomin M

出版信息

Acta Neurol Belg. 1986 Jan-Feb;86(1):11-9.

PMID:3962583
Abstract

Three patients with a post-traumatic spinal cord cavity are described: clinical signs are identical to those of syringomyelia, but pain is more frequent. Diagnosis is made easier by magnetic resonance imaging (MRI) and a syringoperitoneal shunt is proposed for treatment. Nevertheless, if results are good, they seem worse than in idiopathic syringomyelia. The main pathogenic theories are discussed: the rupture and coalescence of microcysts developed at a distance of 1 or 2 mm from the transected spinal cord, subsequently leads to syrinx formation; haemorrhagic or ischemic post-traumatic areas could also lead to syrinx formation. Hydrodynamic factors could be expected and make the pathogenesis not far from syringomyelic one.

摘要

本文描述了3例创伤后脊髓空洞症患者:临床症状与脊髓空洞症相同,但疼痛更为常见。磁共振成像(MRI)使诊断更容易,建议采用脊髓空洞-腹腔分流术进行治疗。然而,即便治疗效果良好,其结果似乎也比特发性脊髓空洞症更差。文中讨论了主要的发病机制理论:在距横断脊髓1或2毫米处形成的微囊肿破裂并融合,随后导致空洞形成;创伤后的出血或缺血区域也可能导致空洞形成。流体动力学因素也可能存在,这使得其发病机制与脊髓空洞症的发病机制相差不远。

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