Nakamura Kentaro, Hirono Kazushi, Iwashita Yume, Nagura Koichi, Okawa Kazuyoshi, Inoue Tatsuya, Asaoka Ryo, Maruyama-Inoue Maiko, Yanagi Yasuo, Kadonosono Kazuaki
Department of Ophthalmology and Micro-Technology, Yokohama City University, 4-57 Urafune, Minami-ku, Yokohama, Kanagawa, 232-0024, Japan.
Department of Ophthalmology, National Defense Medical College Hospital, Saitama, Japan.
Sci Rep. 2024 Dec 4;14(1):30208. doi: 10.1038/s41598-024-76511-w.
We investigated the relationship between time-course changes in the retinal artery angle and metamorphopsia in eyes with idiopathic epiretinal membrane (ERM). Over all, Thirty-seven patients who underwent vitrectomy surgery for ERM were enrolled. In addition to visual acuity (VA), the metamorphopsia score was measured for each eye using M-CHARTS. Moreover, pre- and postoperative retinal artery angle (YCA) was measured using ImageJ software. The difference between pre- and postoperative metamorphopsia score (Mdif), the difference between pre- and postoperative CRT (CRTdif) and the ratio of postoperative YCA to preoperative YCA (pYCA) were calculated and used for the statistical analysis. We investigated the relationship between Mdif and each of age, axial length (AL), pYCA, CRTdif and the follow-up duration. The association of pYCA with Mdif was also investigated in improved VA group (gained at least 0.2 logMAR) and unimproved VA group (gained less than 0.2 logMAR). The logMAR VA and metamorphopsia score significantly improved after vitrectomy surgery (both p < .001). The postoperative YCA was significantly larger than the preoperative YCA (p < .0001). Among age, AL, pYCA, CRTdif and the follow-up duration, pYCA and the follow-up duration were significantly associated with Mdif. Subgroup analysis indicated pYCA was significantly related to Mdif in unimproved VA group, but not in improved VA group. Monitoring the time-course change in the retinal artery angle might be useful for predicting the improvement in metamorphopsia after vitrectomy surgery in ERM eyes.
我们研究了特发性视网膜前膜（ERM）患者视网膜动脉角度的时间进程变化与变形视之间的关系。总共纳入了37例行玻璃体切除术治疗ERM的患者。除视力（VA）外，使用M-CHARTS对每只眼睛测量变形视评分。此外，使用ImageJ软件测量术前和术后的视网膜动脉角度（YCA）。计算术前和术后变形视评分的差值（Mdif）、术前和术后中心视网膜厚度的差值（CRTdif）以及术后YCA与术前YCA的比值（pYCA），并用于统计分析。我们研究了Mdif与年龄、眼轴长度（AL）、pYCA、CRTdif和随访时间之间的关系。还在视力改善组（至少提高0.2 logMAR）和视力未改善组（提高小于0.2 logMAR）中研究了pYCA与Mdif的相关性。玻璃体切除术后，logMAR视力和变形视评分显著改善（均p < .001）。术后YCA显著大于术前YCA（p < .0001）。在年龄、AL、pYCA、CRTdif和随访时间中，pYCA和随访时间与Mdif显著相关。亚组分析表明，pYCA在视力未改善组中与Mdif显著相关，但在视力改善组中不相关。监测视网膜动脉角度的时间进程变化可能有助于预测ERM患者玻璃体切除术后变形视的改善情况。
