Bourmand Raika, Olsson Sofia E, Fijany Arman
Anne Burnett Marion School of Medicine, Texas Christian University Fort Worth Texas USA.
Vanderbilt University Medical Center Nashville Tennessee USA.
Laryngoscope Investig Otolaryngol. 2024 Dec 5;9(6):e70050. doi: 10.1002/lio2.70050. eCollection 2024 Dec.
Total laryngectomy (TL) is a standard induction treatment for laryngeal cancer. Patients have shown decreased quality of life (QOL) following laryngectomy potentially due to its impact on communication. This study is a systematic review of the effects of TEP on QOL in TL patients.
Data was extracted from PubMed, Ovid Medline, and Web of Science. A systematic review of literature assessing QOL after TEP within the last decade was conducted using PRISMA methodology. The initial search yielded 71 publications filtered to 15 after removing duplicates, non-English publications, and title screening. Two researchers independently reviewed abstracts, and 11 articles were retained. After a full article review, 6 examined QOL in TEP patients.
The studies concluded that post-TL, patients with TEP experienced improved QOL than before the procedure or non-TEP alternatives for speech. The collective sample size yielded 253 patients. Meta-analysis demonstrated significant improvement in QOL described by the University of Washington-Quality of Life Index ( < .0001) and insignificant improvement defined by the Voice Handicap Index ( = .07). Several additional indices were included in the articles, all of which indicated improved QOL in TL patients post-TEP. These scales could not undergo meta-analysis due to their presence in only 1 study each.
TEP is a valuable intervention in improving patient QOL and satisfaction following TL. There is no standardized tool for describing QOL in TL patients, so the authors recommend tools be chosen based on the specific aspects of QOL they represent.
2a.
全喉切除术(TL)是喉癌的标准诱导治疗方法。喉切除术后患者的生活质量(QOL)可能会下降,这可能是由于其对交流的影响。本研究是对全喉切除患者中发音重建术(TEP)对生活质量影响的系统评价。
数据从PubMed、Ovid Medline和Web of Science中提取。使用PRISMA方法对过去十年内评估发音重建术后生活质量的文献进行系统评价。初步检索得到71篇出版物,在去除重复、非英文出版物和标题筛选后,筛选至15篇。两名研究人员独立审查摘要,保留11篇文章。在全文审查后,6篇文章研究了发音重建术患者的生活质量。
研究得出结论,全喉切除术后,接受发音重建术的患者的生活质量比手术前或非发音重建术的言语替代方法有所改善。总体样本量为253例患者。荟萃分析表明,华盛顿大学生活质量指数描述的生活质量有显著改善(<0.0001),而嗓音障碍指数定义的改善不显著(=0.07)。文章中还包括了几个其他指标,所有这些指标都表明发音重建术后全喉切除患者的生活质量有所改善。由于这些量表每项仅在1项研究中出现,因此无法进行荟萃分析。
发音重建术是改善全喉切除术后患者生活质量和满意度的一项有价值的干预措施。目前尚无标准化工具来描述全喉切除患者的生活质量,因此作者建议根据工具所代表的生活质量的具体方面来选择工具。
2a。