Mathias J R, Khanna R, Nealon W H, Browne R M, Reeves-Darby V G, Clench M H
Department of Internal Medicine, University of Texas Medical Branch, Galveston 77550.
Dig Dis Sci. 1992 Apr;37(4):545-50. doi: 10.1007/BF01307578.
The Roux-en-Y syndrome was defined as chronic nausea, intermittent vomiting, and chronic abdominal pain worsened by eating in patients who have undergone a gastrojejunostomy Roux-en-Y reconstruction for peptic ulcer. When these patients fasted, the Roux limb showed striking abnormalities in motor function; when postprandial, they failed to convert to normal fed-state motor activity. In contrast, patients with Zollinger-Ellison syndrome do well after similar surgery; they can eat most foods and maintain their body weight. We studied the motility of the Roux limb and jejunum in six patients with Zollinger-Ellison after an esophagojejunostomy Roux-en-Y anastomosis. Roux-limb motor activity in these patients, as characterized by the migrating motor complex, was more frequent, well organized, and in synchrony with the remaining jejunum; most subjects also converted to the fed state after a liquid meal. We suggest that the enteric nervous system is intact and functions normally in patients who have had a Roux-en-Y reconstruction for ulcer disease secondary to Zollinger-Ellison, but not in patients with idiopathic peptic ulcer disease.
鲁氏Y形综合征被定义为，因消化性溃疡接受胃空肠吻合术式鲁氏Y形重建的患者，出现慢性恶心、间歇性呕吐，以及进食后加重的慢性腹痛。这些患者禁食时，鲁氏肠袢在运动功能上表现出显著异常；进食后，其无法转变为正常的进食状态运动活动。相比之下，患有卓-艾综合征的患者在接受类似手术后情况良好；他们能食用大多数食物并维持体重。我们研究了6例接受食管空肠吻合术式鲁氏Y形吻合的卓-艾综合征患者的鲁氏肠袢和空肠的运动情况。这些患者的鲁氏肠袢运动活动，以移行性运动复合波为特征，更为频繁、组织良好，且与其余空肠同步；大多数受试者在进食流食后也转变为进食状态。我们认为，对于因卓-艾综合征继发溃疡病而接受鲁氏Y形重建的患者，其肠神经系统完整且功能正常，但特发性消化性溃疡病患者则不然。
