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用于经颅磁刺激低频电场剂量测定的新型体积积分方程方法

Novel Volume Integral Equation Approach for Low-Frequency E-Field Dosimetry of Transcranial Magnetic Stimulation.

作者信息

Vaezi Seyed Sina, Gomez Luis J

机构信息

Elmore Family School of Electrical and Computer Engineering, Purdue University, 465 Northwestern Ave, West Lafayette, 47907, IN, USA.

出版信息

IEEE Trans Magn. 2024 Dec;60(12). doi: 10.1109/tmag.2024.3486081. Epub 2024 Oct 24.

DOI:10.1109/tmag.2024.3486081
PMID:39649150
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11623319/
Abstract

A new volume integral equation (VIE) approach is introduced to study transcranial magnetic stimulation (TMS) and high-contrast media at low frequencies. This new integral equation offers a simple solution to the high-contrast breakdown observed in low-frequency electric field (E-field) dosimetry of conductive media. Specifically, we employ appropriate approximations that are valid for low frequencies and stabilize the VIE by introducing a basis expansion set that removes solutions associated with high eigenvalues in the equation. The new equation is devoid of high-contrast breakdown and does not require the use of auxiliary surface variables or projectors, providing a straightforward practical solution for the VIE analysis of TMS. Our results indicate that the novel VIE formulation matches boundary element, finite element, and analytical solutions. This new VIE represents a first step towards including anisotropy in integral equation E-field dosimetry for brain stimulation.

摘要

引入了一种新的体积积分方程(VIE)方法来研究低频下的经颅磁刺激(TMS)和高对比度介质。这种新的积分方程为在导电介质的低频电场(E场)剂量学中观察到的高对比度失效问题提供了一个简单的解决方案。具体而言,我们采用了适用于低频的近似方法,并通过引入一个基展开集来稳定VIE,该基展开集消除了方程中与高特征值相关的解。新方程不存在高对比度失效问题,并且不需要使用辅助表面变量或投影算子,为TMS的VIE分析提供了一种直接的实用解决方案。我们的结果表明,这种新颖的VIE公式与边界元、有限元和解析解相匹配。这种新的VIE代表了在用于脑刺激的积分方程E场剂量学中纳入各向异性的第一步。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c51a/11623319/1c644fb9c316/nihms-2038750-f0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c51a/11623319/36eff6732d07/nihms-2038750-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c51a/11623319/dc2c825e145c/nihms-2038750-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c51a/11623319/76e15b9796fa/nihms-2038750-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c51a/11623319/41883d163a5c/nihms-2038750-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c51a/11623319/17617619f076/nihms-2038750-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c51a/11623319/1c644fb9c316/nihms-2038750-f0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c51a/11623319/36eff6732d07/nihms-2038750-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c51a/11623319/dc2c825e145c/nihms-2038750-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c51a/11623319/76e15b9796fa/nihms-2038750-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c51a/11623319/41883d163a5c/nihms-2038750-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c51a/11623319/17617619f076/nihms-2038750-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c51a/11623319/1c644fb9c316/nihms-2038750-f0006.jpg

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本文引用的文献

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Fast and accurate computational E-field dosimetry for group-level transcranial magnetic stimulation targeting.针对群体水平经颅磁刺激靶向的快速准确计算电场剂量学。
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一种用于宽介电常数和大规模电磁分析的蝶形加速体积积分方程求解器。
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