Dahlgren C, Aniansson H, Magnusson K E
Infect Immun. 1985 Jan;47(1):326-8. doi: 10.1128/iai.47.1.326-328.1985.
The stimulation of neutrophils by formylmethionyl-leucyl-phenylalanine results in a bimodal luminol-dependent chemiluminescence pattern. We observed, however, only a single peak chemiluminescence pattern in the response to the peptide when we used lucigenin as an amplifying substance. We suggest that lucigenin, the larger molecule, (510 daltons; luminol is 177 daltons) only exerts an extracellular effect.
甲酰甲硫氨酰-亮氨酰-苯丙氨酸对中性粒细胞的刺激会导致一种双峰的鲁米诺依赖性化学发光模式。然而,当我们使用光泽精作为放大物质时,在对该肽的反应中仅观察到单峰化学发光模式。我们认为,较大的分子光泽精(510道尔顿;鲁米诺为177道尔顿)仅发挥细胞外效应。