Tuo Yanan, He Junchen, Guo Tao
Department of Dermatology, Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin, China.
Medicine (Baltimore). 2024 Dec 6;103(49):e40808. doi: 10.1097/MD.0000000000040808.
Weight-adjusted-waist index (WWI) is an anthropometric indicator of central obesity, which is calculated by dividing the waist circumference (WC) by the squared weight. The purpose of this study was to investigate the association between WWI and psoriasis in adults. Multivariate logistic regression and smoothing curve fitting were used to investigate the relationship between WWI and psoriasis based on data from the National Health and Nutrition Examination Survey (NHANES) 2009 to 2014. Subgroup analysis and interaction tests were employed to examine the population-level stability of this connection. There was a positive association between WWI and psoriasis in 15,932 participants > 20 years of age. In the fully adjusted model, each 1-unit increase in WWI was associated with a 14% increase in the risk of developing psoriasis [1.14 (1.01, 1.32)]. Participants in the highest quartile of WWI had a 38% higher risk of developing psoriasis than those in the lowest quartile [1.38 (1.01, 1.94)]. This positive association was more pronounced in males. WWI is positively associated with psoriasis in US adults. Our findings imply that WWI has the potential to improve psoriasis prevention in the general population.
体重调整腰围指数（WWI）是一种中心性肥胖的人体测量指标，通过腰围（WC）除以体重的平方来计算。本研究的目的是调查WWI与成人银屑病之间的关联。基于2009年至2014年美国国家健康与营养检查调查（NHANES）的数据，采用多因素逻辑回归和平滑曲线拟合来研究WWI与银屑病之间的关系。采用亚组分析和交互作用检验来检验这种关联在人群水平上的稳定性。在15932名年龄大于20岁的参与者中，WWI与银屑病之间存在正相关。在完全调整模型中，WWI每增加1个单位，患银屑病的风险增加14%[1.14（1.01，1.32）]。WWI处于最高四分位数的参与者患银屑病的风险比处于最低四分位数的参与者高38%[1.38（1.01，1.94）]。这种正相关在男性中更为明显。在美国成年人中，WWI与银屑病呈正相关。我们的研究结果表明，WWI有可能改善普通人群中银屑病的预防。
