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干眼抗炎研究的全球研究热点与趋势：文献计量分析（2004 - 2024年）

Global research hotspots and trends in anti-inflammatory studies in dry eye: a bibliometric analysis (2004-2024).

作者信息

Wang Shan, Zheng Wei, Li Ting, Yu Dongxu, Zhang Qi, Ju Yuan, Wei Lijuan

机构信息

College of Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Jilin, China.

Ophthalmology Department, Affiliated Hospital of Changchun University of Traditional Chinese Medicine, Changchun, Jilin, China.

出版信息

Front Med (Lausanne). 2024 Nov 28;11:1451990. doi: 10.3389/fmed.2024.1451990. eCollection 2024.

DOI:10.3389/fmed.2024.1451990
PMID:39669988
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11634594/
Abstract

BACKGROUND

Inflammation plays a crucial role in the pathophysiology of dry eye (DE). This study aims to provide a comprehensive overview of the current status, hotspots and trends in DE anti-inflammatory research through bibliometric analysis.

METHOD

All publications were searched using the Web of Science Core Collection (WoSCC) database from 2004 to 2024. Bibliometric analyses were performed using VOSviewer, R-bibliometrix, and CiteSpace, and data were managed using Microsoft Office Excel 2019.

RESULTS

There were 603 papers published between 2004 and 2024 included in this study, with the number of papers increasing each year. The United States was the major contributor, with the largest number of publications and the greatest impact. Baylor College of Medicine was the most influential research institution. Pflugfelder, Stephen C. and Tsubota, Kazuo were the most prolific authors in this area of research, while Dana, Reza was the most cited author in the field with the highest impact. The Journal with the highest number of publications was , while the highest impact journal was . Research hotspots were focused on the mechanisms of inflammation in DE and interventions for anti-inflammatory therapy. Future studies would favor more inflammation-related targeted therapies and physical therapies.

CONCLUSION

This study is the first bibliometric analysis to comprehensively summarize research trends and developments in DE anti-inflammatory treatments, pointing out recent research frontiers and hot directions for scholars studying DE anti-inflammatory treatments.

摘要

背景

炎症在干眼（DE）的病理生理学中起着关键作用。本研究旨在通过文献计量分析全面概述DE抗炎研究的现状、热点和趋势。

方法

使用Web of Science核心合集（WoSCC）数据库检索2004年至2024年的所有出版物。使用VOSviewer、R-bibliometrix和CiteSpace进行文献计量分析，并使用Microsoft Office Excel 2019管理数据。

结果

本研究纳入了2004年至2024年间发表的603篇论文，论文数量逐年增加。美国是主要贡献者，发表数量最多且影响力最大。贝勒医学院是最具影响力的研究机构。Pflugfelder, Stephen C.和Tsubota, Kazuo是该研究领域最多产的作者，而Dana, Reza是该领域被引次数最多、影响力最高的作者。发表论文数量最多的期刊是 ，而影响力最高的期刊是 。研究热点集中在DE的炎症机制和抗炎治疗干预措施上。未来的研究将倾向于更多与炎症相关的靶向治疗和物理治疗。

结论

本研究是首次全面总结DE抗炎治疗研究趋势和进展的文献计量分析，为研究DE抗炎治疗的学者指出了近期的研究前沿和热门方向。

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