Ghonaim Ahmed H, Rouby Sherin R, Nageeb Wedad M, Elgendy Ashraf Ahmed, Xu Rong, Jiang Changsheng, Ghonaim Noha H, He Qigai, Li Wentao
National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China; The Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China; Desert Research Center, Cairo 11435, Egypt.
Department of Veterinary Medicine, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef 62511, Egypt.
Virol Sin. 2025 Feb;40(1):1-14. doi: 10.1016/j.virs.2024.12.001. Epub 2024 Dec 11.
Rotavirus infections cause severe gastroenteritis and dehydration in young children and animals worldwide, leading to high rates of morbidity and mortality, predominantly in low- and middle-income countries. In the past decade, substantial progress has been made in the development and implementation of rotavirus vaccines, which have been essential in alleviating the global burden of this disease, not only in human being but also in livestock species like calves and piglets, where these infections can cause significant economic losses. By synthesizing the latest research and real-world evidence, this review article is designated to provide deep insights into the current state of rotavirus vaccine technology and its global implementation as well as the application of rotavirus vaccines in veterinary settings and their importance in controlling zoonotic transmission and maintaining food security.
轮状病毒感染在全球范围内导致幼儿和动物严重的胃肠炎和脱水，导致高发病率和死亡率，主要发生在低收入和中等收入国家。在过去十年中，轮状病毒疫苗的研发和应用取得了重大进展，这对于减轻这种疾病的全球负担至关重要，不仅对人类，而且对小牛和仔猪等家畜物种也是如此，这些感染会造成重大经济损失。通过综合最新研究和实际证据，这篇综述文章旨在深入洞察轮状病毒疫苗技术的现状及其全球应用，以及轮状病毒疫苗在兽医领域的应用及其在控制人畜共患病传播和维护粮食安全方面的重要性。
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