Alotaibi Hend M, Alghamdi Asail S, Almutairi Rahaf Tayi, Altamimi Rawan Mousa, Osailan Raha
Dermatology Department, King Saud University, Riyadh, Saudi Arabia.
Dermatology Department, King Fahad Hospital, Albaha, Saudi Arabia.
Arch Dermatol Res. 2024 Dec 16;317(1):132. doi: 10.1007/s00403-024-03613-w.
Chronic idiopathic urticaria (CIU) is difficult for patients and healthcare professionals to manage owing to its chronic and unpredictable nature. While the exact cause of CIU is unknown, it is suggested that food allergies may contribute to the development of symptoms. To determine the prevalence of food allergy in patients diagnosed with CIU. This systematic review is reported in accordance with PRISMA guidelines. We included all relevant articles published from inception to April 2023 in Scopus, Midline, and Web of Science. The initial search yielded 282 articles, of which only seven were included after applying the inclusion and exclusion criteria. The systematic review included a total of 1551 patients with urticaria. Approximately 25% of patients with food allergies had CIU. The prevalence of a family history of atopy was 37.9% (range, 24.3-53.8%, P = 0.133). There was a significant risk of angioedema in patients with urticaria (P = 0.039). The risk of CIU among patients with food allergies was estimated to be one in every four patients with urticaria, with a similar risk among the adult and pediatric populations. Patients with food allergies and a history of atopy were at higher risk of CIU. Angioedema is a common concomitant manifestation associated with common urticaria. This knowledge is important to identify patients at higher risk of urticaria and implement the necessary management to minimize potential complications and maintain a controlled disease.
慢性特发性荨麻疹（CIU）因其慢性和不可预测的性质，给患者和医护人员的管理带来了困难。虽然CIU的确切病因尚不清楚，但有观点认为食物过敏可能导致症状的出现。为了确定CIU患者中食物过敏的患病率。本系统评价按照PRISMA指南进行报告。我们纳入了从创刊到2023年4月在Scopus、Medline和科学网发表的所有相关文章。初步检索得到282篇文章，应用纳入和排除标准后仅纳入7篇。该系统评价共纳入1551例荨麻疹患者。约25%的食物过敏患者患有CIU。特应性家族史的患病率为37.9%（范围为24.3 - 53.8%，P = 0.133）。荨麻疹患者发生血管性水肿的风险显著（P = 0.039）。食物过敏患者中CIU的风险估计为每4例荨麻疹患者中有1例，成人和儿童人群中的风险相似。有食物过敏和特应性病史的患者患CIU的风险更高。血管性水肿是与普通荨麻疹相关的常见伴随表现。这些知识对于识别荨麻疹高风险患者并实施必要管理以尽量减少潜在并发症和维持疾病控制非常重要。
