Islam Anowarul, Islam Md Sadikul, Rahman Md Khalesur, Uddin Md Nazim, Akanda Md Rashedunnabi
College of Veterinary Medicine, Jeonbuk National University, Iksan, 54596, South Korea.
Department of Microbiology, Faculty of Veterinary and Animal Science, Hajee Mohammad Danesh Science and Technology University, Dinajpur, 5200, Bangladesh.
Arch Pharm Res. 2020 Jun;43(6):582-592. doi: 10.1007/s12272-020-01243-0. Epub 2020 Jun 27.
Eriodictyol is a flavonoid in the flavanones subclass. It is abundantly present in a wide range of medicinal plants, citrus fruits, and vegetables that are considered to have potential health importance. Having the considerable medicinal properties, eriodictyol has been predicted to clarify the mode of action in various cellular and molecular pathways. Evidence for the existing therapeutic roles of eriodictyol includes antioxidant, anti-inflammatory, anti-cancer, neuroprotective, cardioprotective, anti-diabetic, anti-obesity, hepatoprotective, and miscellaneous. Therefore, this review aims to present the recent evidence regarding the mechanisms of action of eriodictyol in different signaling pathways in a specific disease condition. In view of the immense therapeutic effects, eriodictyol may serve as a potential drug source to enhance community health standards.
圣草酚是黄烷酮亚类中的一种黄酮类化合物。它大量存在于多种具有潜在健康重要性的药用植物、柑橘类水果和蔬菜中。由于具有相当的药用特性，预计圣草酚能阐明各种细胞和分子途径中的作用模式。圣草酚现有治疗作用的证据包括抗氧化、抗炎、抗癌、神经保护、心脏保护、抗糖尿病、抗肥胖、肝脏保护等多种作用。因此，本综述旨在介绍有关圣草酚在特定疾病状态下不同信号通路中作用机制的最新证据。鉴于其巨大的治疗效果，圣草酚可能成为提高社区健康水平的潜在药物来源。
