Deng Zirong, Hassan Sabba, Rafiq Muhammad, Li Hongshui, He Yang, Cai Yi, Kang Xi, Liu Zhaoguo, Yan Tingdong
School of Pharmacy, Nantong University, 19 Qixiu Road, Nantong, Jiangsu 226001, China.
Department of Physiology and Biochemistry, Cholistan University of Veterinary and Animal Sciences (CUVAS), Bahawalpur 63100, Pakistan.
Evid Based Complement Alternat Med. 2020 Dec 12;2020:6681352. doi: 10.1155/2020/6681352. eCollection 2020.
Eriodictyol is a flavonoid that belongs to a subclass of flavanones and is widespread in citrus fruits, vegetables, and medicinally important plants. Eriodictyol has been anticipated to explain the method of its activity via multiple cellular signaling cascades. Eriodictyol is an effective natural drug source to maintain higher health standards due to its excellent therapeutic roles in neuroprotection, cardioprotective activity, hepatoprotective activity, antidiabetes and obesity, and skin protection and having highly analgesic, antioxidant, and anti-inflammatory effects, antipyretic and antinociceptive actions, antitumor activity, and much more. This review aims to highlight the modes of action of eriodictyol against various diseases via multiple cellular signaling pathways.
圣草酚是一种黄酮类化合物，属于黄烷酮的一个亚类，广泛存在于柑橘类水果、蔬菜和具有重要药用价值的植物中。人们预计圣草酚可通过多种细胞信号级联反应来解释其活性机制。由于圣草酚在神经保护、心脏保护活性、肝脏保护活性、抗糖尿病和肥胖以及皮肤保护方面具有出色的治疗作用，并且具有高度的镇痛、抗氧化和抗炎作用、解热和抗伤害感受作用、抗肿瘤活性等，因此它是维持更高健康标准的有效天然药物来源。本综述旨在强调圣草酚通过多种细胞信号通路对抗各种疾病的作用模式。
