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来自杂色曲霉的代谢产物5,6-二甲氧基柄曲霉素在沙门氏菌/微粒体系统中的致突变性。

Mutagenicity of 5,6-dimethoxysterigmatocystin, a metabolite from Aspergillus multicolor, in the Salmonella/microsome system.

作者信息

Wehner F C, Thiel P G, Vleggaar R

出版信息

Appl Environ Microbiol. 1979 Nov;38(5):1015-7. doi: 10.1128/aem.38.5.1015-1017.1979.

Abstract

The natural sterigmatocystin derivative, 5,6-dimethoxysterigmatocystin, was found to be a mutagen for Salmonella typhimurium strains TA98 and TA100 after metabolic activation in a mammalian microsome system.

摘要

天然柄曲霉素衍生物5,6-二甲氧基柄曲霉素,在哺乳动物微粒体系统中经代谢活化后,被发现对鼠伤寒沙门氏菌TA98和TA100菌株具有致突变性。

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本文引用的文献

1
Mycotoxins in Aspergillus.
Mycopathol Mycol Appl. 1971 Feb 19;43(2):137-52. doi: 10.1007/BF02051714.
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Production of sterigmatocystin by some species of the genus Aspergillus and its toxicity to chicken embryos.
Appl Microbiol. 1975 Oct;30(4):589-91. doi: 10.1128/am.30.4.589-591.1975.
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Mutagenicity of aflatoxins related to their metabolism and carcinogenic potential.
Proc Natl Acad Sci U S A. 1976 Jul;73(7):2241-4. doi: 10.1073/pnas.73.7.2241.
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Mutagenicity to Salmonella typhimurium of some Aspergillus and Penicillium mycotoxins.
Mutat Res. 1978 Nov;58(2-3):193-203. doi: 10.1016/0165-1218(78)90009-5.

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