Wang Cheng-Lin, Xue Zhe-Yong, Liu Juan, Hua Xin
College of Life Sciences, Northeast Forestry University Harbin 150006, China State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
College of Life Sciences, Northeast Forestry University Harbin 150006, China.
Zhongguo Zhong Yao Za Zhi. 2024 Nov;49(22):6048-6065. doi: 10.19540/j.cnki.cjcmm.20240812.203.
The genus Eleutherococcus includes multiple medicinal plants that hold significant value in the fields of medicine, health, economy, and food. The resources of this genus are widely distributed and rich in secondary metabolites. The secondary metabolites reported in Eleutherococcus plants include various types, such as terpenoids, phenolic acids, flavonoids, and lignans, which exhibit pharmacological activities such as anti-inflammatory, anti-tumor, antioxidant, and neuroprotective effects. Among these, the triterpenoid components in Eleutherococcus plants have garnered significant attention. This review summarized the research progress on the resource distribution, species classification, secondary metabolites, and pharmacological activities of Eleutherococcus plants and discussed their ecological significance, pharmacological development, and future research directions, with the aim of providing references for species conservation, drug development, and disease treatment involving Eleutherococcus plants.
刺五加属包含多种药用植物，在医药、健康、经济和食品领域具有重要价值。该属植物资源分布广泛，富含次生代谢产物。刺五加属植物中报道的次生代谢产物包括多种类型，如萜类、酚酸、黄酮类和木脂素类，它们具有抗炎、抗肿瘤、抗氧化和神经保护等药理活性。其中，刺五加属植物中的三萜类成分备受关注。本文综述了刺五加属植物的资源分布、物种分类、次生代谢产物和药理活性的研究进展，并探讨了它们的生态意义、药理开发及未来研究方向，旨在为涉及刺五加属植物的物种保护、药物研发和疾病治疗提供参考。
