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植物学、植物化学与药理学综述。

: Review of Botany, Phytochemistry and Pharmacology.

机构信息

National Engineering Research Center for Modernization of Traditional Chinese Medicine-Hakka Medical Resources Branch, School of Pharmacy, Gannan Medical University, Ganzhou 341000, China.

School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China.

出版信息

Molecules. 2021 Apr 12;26(8):2215. doi: 10.3390/molecules26082215.

Abstract

(Oliv.) Harms (Araliaceae), also known as and () in Chinese, is a widely used traditional Chinese herb with the effects of expelling wind and removing dampness, relaxing the muscles and stimulating the blood circulation, and regulating the flow of to alleviate pain in the theory of Traditional Chinese Medicine. (AH, thereafter) possesses ginseng-like activities and is known as ginseng-like herb. In the past decade, a great number of phytochemical and pharmacological studies on AH have been carried out. Several kinds of chemical compositions have been reported, including terpenoids (monoterpenoids, diterpenoids, and triterpenoid saponins), phenylpropanoids, caffeoyl quinic acid derivatives, flavonoids, lignans, sterols, fatty acids, etc., among which, triterpenoid saponins were considered to be the most active components. Considerable pharmacological experiments in vitro have demonstrated that AH possessed anti-neuroinflammatory, anti-adipogenic, anti-inflammatory, antibacterial, anti-cancer, anti-oxidation, anti-AChE, anti-BuChE, and antihyaluronidase activities. The present review is an up-to-date and comprehensive analysis of the botany, phytochemistry, and pharmacology of AH.

摘要

(Oliv.)Harms(伞形科),中文也称为 和 ,是一种广泛使用的传统中药,具有祛风除湿、舒筋活血、通经止痛的功效,在中医理论中。(AH,以下简称)具有类似人参的作用,被称为人参样草药。在过去的十年中,对 AH 进行了大量的植物化学和药理学研究。已经报道了几种化学成分,包括萜类(单萜、二萜和三萜皂苷)、苯丙素、咖啡酰奎宁酸衍生物、类黄酮、木脂素、甾醇、脂肪酸等,其中三萜皂苷被认为是最活跃的成分。大量的体外药理学实验表明,AH 具有抗神经炎症、抗脂肪生成、抗炎、抗菌、抗癌、抗氧化、抗 AChE、抗 BuChE 和抗透明质酸酶活性。本综述是对 AH 的植物学、植物化学和药理学的最新和全面的分析。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/145d/8069704/01520febf2db/molecules-26-02215-g001.jpg

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