• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

这二十年来对肠道微生物群的研究是否带来了更健康的选择?

Has the two decades of research on the gut microbiome resulted in making healthier choices?

作者信息

Azcarate-Peril M Andrea

机构信息

Center for Gastrointestinal Biology and Disease (CGIBD), Department of Medicine, Division of Gastroenterology and Hepatology, School of Medicine, UNC Microbiome Core, University of North Carolina, Chapel Hill, NC, USA.

出版信息

Gut Microbiome (Camb). 2024 Dec 2;5:e10. doi: 10.1017/gmb.2024.13. eCollection 2024.

DOI:10.1017/gmb.2024.13
PMID:39703542
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11658936/
Abstract

The gut microbiome is widely recognized for its significant contribution to maintaining human health across all life stages, from infancy to adulthood and beyond. This perspective article focuses on the impacts of well-supported microbiome research on global caesarean delivery rates, breastfeeding practices, and antimicrobial use. The article also explores the impact of dietary choices, particularly those involving ultra-processed foods, on the gut microbiota and their potential contribution to conditions like obesity, metabolic syndrome, and inflammatory diseases. This perspective aims to emphasize the need for updated guidelines and policy interventions to address the increasing global trends of caesarean deliveries, reduced breastfeeding, overuse of antibiotics, and consumption of highly processed foods to counter their adverse effects on gut health.

摘要

肠道微生物群因其在从婴儿期到成年期及以后的所有生命阶段对维持人类健康的重大贡献而广受认可。这篇观点文章重点关注了有充分证据支持的微生物群研究对全球剖宫产率、母乳喂养实践和抗菌药物使用的影响。文章还探讨了饮食选择,特别是那些涉及超加工食品的选择,对肠道微生物群的影响以及它们对肥胖、代谢综合征和炎症性疾病等病症的潜在影响。这一观点旨在强调需要更新指南和政策干预措施,以应对全球剖宫产率上升、母乳喂养减少、抗生素过度使用以及高加工食品消费增加的趋势,以对抗它们对肠道健康的不利影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5a0/11658936/e83daf19bd71/S2632289724000136_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5a0/11658936/e83daf19bd71/S2632289724000136_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5a0/11658936/e83daf19bd71/S2632289724000136_fig1.jpg

相似文献

1
Has the two decades of research on the gut microbiome resulted in making healthier choices?这二十年来对肠道微生物群的研究是否带来了更健康的选择?
Gut Microbiome (Camb). 2024 Dec 2;5:e10. doi: 10.1017/gmb.2024.13. eCollection 2024.
2
The gut microbiome across the lifespan: how diet modulates our microbial ecosystem from infancy to the elderly.一生中的肠道微生物群:饮食如何从婴儿期到老年期调节我们的微生物生态系统。
Int J Food Sci Nutr. 2025 Mar;76(2):95-121. doi: 10.1080/09637486.2024.2437472. Epub 2024 Dec 19.
3
Birth Mode Does Not Determine the Presence of Shared Bacterial Strains between the Maternal Vaginal Microbiome and the Infant Stool Microbiome.分娩方式并不会决定母婴阴道微生物群和婴儿粪便微生物群之间的细菌菌株共享。
Microbiol Spectr. 2023 Aug 17;11(4):e0061423. doi: 10.1128/spectrum.00614-23. Epub 2023 Jun 20.
4
Diet-microbiota interaction in irritable bowel syndrome: looking beyond the low-FODMAP approach.饮食-微生物群相互作用在肠易激综合征中的作用:超越低 FODMAP 方法。
Scand J Gastroenterol. 2023 Jul-Dec;58(12):1366-1377. doi: 10.1080/00365521.2023.2228955. Epub 2023 Jun 29.
5
Ultra-Processed Foods: A Narrative Review of the Impact on the Human Gut Microbiome and Variations in Classification Methods.超加工食品:对人类肠道微生物组影响的叙述性综述及分类方法的差异。
Nutrients. 2024 Jun 1;16(11):1738. doi: 10.3390/nu16111738.
6
The role of antibiotic exposure and the effects of breastmilk and human milk feeding on the developing infant gut microbiome.抗生素暴露的作用以及母乳和人乳喂养对发育中婴儿肠道微生物组的影响。
Front Public Health. 2024 Jun 6;12:1408246. doi: 10.3389/fpubh.2024.1408246. eCollection 2024.
7
Effect of ultra-processed food consumption on the gut microbiota in the first year of life: Findings from the MINA-Brazil birth cohort study.超加工食品消费对生命第一年肠道微生物群的影响:巴西MINA出生队列研究的结果
Clin Nutr. 2025 Mar;46:181-190. doi: 10.1016/j.clnu.2025.01.030. Epub 2025 Feb 6.
8
Impact of maternal intrapartum antibiotics, method of birth and breastfeeding on gut microbiota during the first year of life: a prospective cohort study.产妇产时抗生素使用、分娩方式和母乳喂养对生命第一年肠道微生物群的影响:一项前瞻性队列研究。
BJOG. 2016 May;123(6):983-93. doi: 10.1111/1471-0528.13601. Epub 2015 Sep 28.
9
The Detrimental Impact of Ultra-Processed Foods on the Human Gut Microbiome and Gut Barrier.超加工食品对人体肠道微生物群和肠道屏障的有害影响。
Nutrients. 2025 Feb 28;17(5):859. doi: 10.3390/nu17050859.
10
Unveiling the Gut Microbiome: How Junk Food Impacts the Gut.揭开肠道微生物群的奥秘:垃圾食品如何影响肠道。
Cureus. 2023 Nov 21;15(11):e49179. doi: 10.7759/cureus.49179. eCollection 2023 Nov.

本文引用的文献

1
The interplay between diet and the gut microbiome: implications for health and disease.饮食与肠道微生物组的相互作用:对健康和疾病的影响。
Nat Rev Microbiol. 2024 Nov;22(11):671-686. doi: 10.1038/s41579-024-01068-4. Epub 2024 Jul 15.
2
Is There Evidence to Support Probiotic Use for Healthy People?是否有证据支持健康人群使用益生菌?
Adv Nutr. 2024 Aug;15(8):100265. doi: 10.1016/j.advnut.2024.100265. Epub 2024 Jul 6.
3
Galacto-Oligosaccharides and the Elderly Gut: Implications for Immune Restoration and Health.半乳糖寡糖与老年肠道:对免疫恢复和健康的影响。
Adv Nutr. 2024 Aug;15(8):100263. doi: 10.1016/j.advnut.2024.100263. Epub 2024 Jun 17.
4
Ultra-Processed Foods: A Narrative Review of the Impact on the Human Gut Microbiome and Variations in Classification Methods.超加工食品:对人类肠道微生物组影响的叙述性综述及分类方法的差异。
Nutrients. 2024 Jun 1;16(11):1738. doi: 10.3390/nu16111738.
5
Exposure to environmental pollutants selects for xenobiotic-degrading functions in the human gut microbiome.暴露于环境污染物会选择人类肠道微生物组中的异生物质降解功能。
Nat Commun. 2024 May 27;15(1):4482. doi: 10.1038/s41467-024-48739-7.
6
Nutritional Criminology: Why the Emerging Research on Ultra-Processed Food Matters to Health and Justice.营养犯罪学:为什么关于超加工食品的新兴研究对健康和正义很重要。
Int J Environ Res Public Health. 2024 Jan 23;21(2):120. doi: 10.3390/ijerph21020120.
7
Ultra-processed foods and food additives in gut health and disease.超加工食品和食品添加剂与肠道健康和疾病。
Nat Rev Gastroenterol Hepatol. 2024 Jun;21(6):406-427. doi: 10.1038/s41575-024-00893-5. Epub 2024 Feb 22.
8
U.S. Policies Addressing Ultraprocessed Foods, 1980-2022.美国 1980-2022 年针对超加工食品的政策。
Am J Prev Med. 2023 Dec;65(6):1134-1141. doi: 10.1016/j.amepre.2023.07.006. Epub 2023 Jul 13.
9
Evaluating the relationship between community water and sanitation access and the global burden of antibiotic resistance: an ecological study.评估社区水和环境卫生设施的获得情况与抗生素耐药性全球负担之间的关系:一项生态学研究。
Lancet Microbe. 2023 Aug;4(8):e591-e600. doi: 10.1016/S2666-5247(23)00137-4. Epub 2023 Jun 30.
10
Maternal and food microbial sources shape the infant microbiome of a rural Ethiopian population.母体和食物微生物来源塑造了埃塞俄比亚农村人口婴儿的微生物组。
Curr Biol. 2023 May 22;33(10):1939-1950.e4. doi: 10.1016/j.cub.2023.04.011. Epub 2023 Apr 27.