探索无血清培养基开发的成本降低策略。
Exploring cost reduction strategies for serum free media development.
作者信息
Quek Jun Ping, Gaffoor Azra Anwar, Tan Yu Xuan, Tan Tessa Rui Min, Chua Yu Feng, Leong Dawn Sow Zong, Ali Alif Sufiyan, Ng Say Kong
机构信息
Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01 Centros, Singapore, 138668, Republic of Singapore.
出版信息
NPJ Sci Food. 2024 Dec 21;8(1):107. doi: 10.1038/s41538-024-00352-0.
Cultivated meat production offers solutions in addressing global food security and sustainability challenges. However, serum-free media (SFM) used in cultivating the cells are expensive, contributing to at least 50% of variable operating costs. This review explores technologies for cost-effective SFM, focusing on reducing cost from using growth factors and recombinant proteins, using affordable raw materials for basal media, and implementing cost-saving measures like media recycling and reducing waste build-up.
实验室培养肉的生产为应对全球粮食安全和可持续发展挑战提供了解决方案。然而，用于培养细胞的无血清培养基（SFM）成本高昂，至少占可变运营成本的50%。本综述探讨了具有成本效益的无血清培养基技术，重点是降低生长因子和重组蛋白的使用成本、使用价格合理的基础培养基原料，以及实施诸如培养基回收利用和减少废物堆积等节约成本的措施。
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