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在使用和不使用导尿管的人群中,我们能否在不使用抗生素的情况下预防复发性尿路感染?ICI-RS 2024。

Can We Prevent Recurrent UTIs Without Antibiotics, in Both Those Who Do and Do Not Use Catheters? ICI-RS 2024.

作者信息

Harding Christopher, Clavica Francesco, Averbeck Marcio Augusto, Da Silva Anasofia, Drake Marcus John, Gajewski Jerzy Bogdan, Khullar Vik, Pozniak Michael, Rantell Angie Marie, Tarcan Tufan, Werneburg Glenn Thomas, Giarenis Ilias

机构信息

Department of Urology, Freeman Hospital, Newcastle-upon-Tyne, UK.

Translational and Clinical Research Institute, Newcastle University, Newcastle-upon-Tyne, UK.

出版信息

Neurourol Urodyn. 2025 Mar;44(3):637-643. doi: 10.1002/nau.25641. Epub 2024 Dec 24.

Abstract

AIMS

Urinary tract infections are one of the most common reasons for antibiotic prescription. The widespread use of antibiotic treatments contributes to the global health problem of antimicrobial resistance development. To slow down the progression of antimicrobial resistance, it is essential that we explore nonantibiotic preventive treatments for this common condition. We aim to report discussions regarding nonantibiotic preventive strategies for recurrent urinary tract infections in both catheterized and non-catheterized patients that took place at the International Consultation on Incontinence-Research Society meeting in Bristol in 2024.

METHODS

We undertook a think-tank session during this multidisciplinary meeting specifically designated for discussion regarding both established and emerging nonantibiotic treatments for UTI prevention in both catheterized and non-catheterized patients. This led to the generation of pertinent research questions, which hope to shape future UTI research.

RESULTS

We describe the discussions that took place and document the important research questions that were proposed during the International Consultation on Incontinence-Research Society meeting in Bristol in 2024.

CONCLUSIONS

There is a range of established UTI preventative strategies for UTI prevention in both catheterized and non-catheterized patients. Emerging UTI prevention treatments have varying levels of evidence to support their use, and in many areas, further research is needed to establish their place in clinical pathways.

摘要

目的

尿路感染是抗生素处方最常见的原因之一。抗生素治疗的广泛使用导致了抗菌药物耐药性这一全球健康问题的出现。为减缓抗菌药物耐药性的发展,探索针对这种常见病症的非抗生素预防性治疗至关重要。我们旨在报告2024年在布里斯托尔举行的国际尿失禁咨询会——研究学会会议上,关于导尿和非导尿患者复发性尿路感染的非抗生素预防策略的讨论情况。

方法

在这次多学科会议期间,我们举办了一次智囊团会议,专门讨论针对导尿和非导尿患者预防尿路感染的既定和新兴非抗生素治疗方法。这产生了相关的研究问题,有望为未来的尿路感染研究指明方向。

结果

我们描述了会议期间进行的讨论,并记录了在2024年布里斯托尔举行的国际尿失禁咨询会——研究学会会议上提出的重要研究问题。

结论

对于导尿和非导尿患者预防尿路感染,有一系列既定的预防策略。新兴的尿路感染预防治疗方法有不同程度的证据支持其使用,在许多领域,还需要进一步研究以确定它们在临床路径中的地位。

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