两种检测风疹感染免疫力检测方法的评估与比较
Evaluation and comparison of two assays for detection of immunity to rubella infection.
作者信息
Brody J P, Binkley J H, Harding S A
出版信息
J Clin Microbiol. 1979 Nov;10(5):708-11. doi: 10.1128/jcm.10.5.708-711.1979.
Abstract
Two commercially available rapid screening tests, Rubacell (Abbott Laboratories; passive hemagglutination) and FIAX (International Diagnostic Technology; indirect immunofluorescence) were compared with a standard hemagglutination inhibition assay for detection of immunity to rubella infection. In tests of approximately 300 sera, both rapid assays were specific and sensitive and showed a high predictive value of a positive result. Within-run reproducibility studies were excellent for both tests; however, Rubacell was superior to FIAX with respect to time-cost analysis.
摘要
将两种市售快速筛查试验，即鲁巴塞尔（雅培实验室；被动血凝试验）和FIAX（国际诊断技术公司；间接免疫荧光法）与标准血凝抑制试验进行比较，以检测风疹感染的免疫力。在对大约300份血清的检测中，两种快速检测方法均具有特异性和敏感性，且阳性结果的预测价值很高。两种检测方法的批内重复性研究结果都很好；然而，在时间成本分析方面，鲁巴塞尔优于FIAX。
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