Kota Sobha, Dumpala Pradeep, Sajja Radhika, Anantha Ratnakumari
Department of Chemical Engineering, RVR & JC College of Engineering (A), Guntur, Andhra Pradesh, 522019, India.
Department of Mechanical Engineering, RVR & JC College of Engineering (A), Guntur, Andhra Pradesh, 522019, India.
Sci Rep. 2024 Dec 28;14(1):30857. doi: 10.1038/s41598-024-81169-5.
The study analyzed the aqueous leaf extracts of Moringa oleifera and Musa sps. for phytochemical components, including flavonoids, sterols, saponins, tannins, and glycosides. The LC-MS analysis revealed gingerol, vicenin-2, caffeic acid, quercetin, and other compounds in the extracts. The synthesized MO- and MS- CuNPs (copper nanoparticles) exhibited plasmon resonance at 320 and 480 nm respectively, and Cu(II)-O stretching vibrations, manifested by their Fourier Transform Infrared (FT-IR) spectra. Thermogravimetric analysis showed that MO-/MS-CuNPs experienced a total weight loss of 80.2% and 68% respectively. Further, the EDS analysis revealed that MO-CuNPs have a copper content of 20%, while MS-CuNPs is 32%. The X-ray diffraction (XRD) patterns of the annealed MO and MS-CuNPs indicate the presence of both the cubic phase of copper (Cu) and the monoclinic tenorite phase of copper oxide (CuO). The percent DPPH scavenging activity of MO- and MS-CuNPs is 34.4 and 28.8, and by KMnO is 63.8 and 47.3% respectively. The behavior of CuNPs exhibited an asymmetrical response, with greater inhibition of Gram-negative bacteria compared to Gram-positive bacteria. CuNPs and medicinal plant-derived carbon dots were integrated into nanofibrous electrospun biopolymer scaffolds for wound care, demonstrating 100% wound healing in Yorkshire pigs full thickness excision wounds after 34 days.
该研究分析了辣木和芭蕉属植物的水叶提取物中的植物化学成分，包括黄酮类、甾醇类、皂苷类、单宁类和糖苷类。液相色谱 - 质谱分析揭示了提取物中的姜辣素、异荭草苷 -2、咖啡酸、槲皮素和其他化合物。合成的MO - CuNPs（铜纳米颗粒）和MS - CuNPs分别在320和480 nm处表现出等离子体共振，并通过傅里叶变换红外（FT - IR）光谱表现出Cu（II） - O伸缩振动。热重分析表明，MO - CuNPs和MS - CuNPs的总重量损失分别为80.2%和68%。此外，能谱分析表明，MO - CuNPs的铜含量为20%，而MS - CuNPs为32%。退火后的MO - CuNPs和MS - CuNPs的X射线衍射（XRD）图谱表明存在铜（Cu）的立方相和氧化铜（CuO）的单斜晶系赤铜矿相。MO - CuNPs和MS - CuNPs的DPPH清除活性百分比分别为34.4和28.8，通过高锰酸钾法测定分别为63.8和47.3%。CuNPs的行为表现出不对称反应，对革兰氏阴性菌的抑制作用比对革兰氏阳性菌更强。将CuNPs和药用植物衍生的碳点整合到用于伤口护理的纳米纤维静电纺丝生物聚合物支架中，在34天后，约克郡猪的全层切除伤口实现了100%的伤口愈合。
