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两种具有重要民族药用价值的植物的抗菌潜力及植物化学分析

Antibacterial potential and phytochemical analysis of two ethnomedicinally important plants.

作者信息

Singh Narpat, Chhangani Neha, Bissa Sharad

机构信息

Microbiology and Plant Pathology Laboratory, Department of Botany, Jai Narain Vyas University, Jodhpur, Rajasthan, India.

出版信息

Curr Res Microb Sci. 2024 Nov 10;8:100297. doi: 10.1016/j.crmicr.2024.100297. eCollection 2025.

DOI:10.1016/j.crmicr.2024.100297
PMID:39735720
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11681831/
Abstract

Medicinal plants exhibited great role in drug industries. Herbal medicines and their derivative products are often prepared from crude plant extracts. and both are belonging to Asteraceae family and these plants are ethnomedicinally important due to their utilization as traditional medicine to cure various diseases. Aim of the current study is to evaluate the antimicrobial properties, preliminary phytochemical and GC-MS analysis of these ethnomedicinally important plants to identify the compounds which are responsible for antimicrobial properties. Their extracts exhibited antimicrobial activity against and . Both plants contain the active principles like flavonoids, alkaloids, glycosides, saponins, terpenoids and tannins. Result of GC-MS analysis showed the presence of many compounds such as n-Hexadecanoic acid, Hexadecanoic Acid, Methyl ester, Octadecanoic acid, Stigmasterol, Naphthalene, Squalene, 4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl-, Squalene, 4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl-,5 Hydroxymethylfurfural, Lupeol, Dodecanoic acid, Vitamin E (α-Tocopherol), Neophytadiene, Phytol and many other compounds. These compounds are responsible for antimicrobial, anticancer and medicinal properties.

摘要

药用植物在制药行业中发挥着重要作用。草药及其衍生产品通常由植物粗提取物制备而成。这两种植物都属于菊科,由于它们被用作治疗各种疾病的传统药物,因此在民族医学中具有重要意义。本研究的目的是评估这些具有民族医学重要性的植物的抗菌特性、初步植物化学分析和气相色谱-质谱联用(GC-MS)分析,以鉴定具有抗菌特性的化合物。它们的提取物对[具体菌种1]和[具体菌种2]表现出抗菌活性。这两种植物都含有黄酮类、生物碱、糖苷、皂苷、萜类和单宁等活性成分。GC-MS分析结果显示存在许多化合物,如正十六烷酸、十六烷酸甲酯、十八烷酸、豆甾醇、萘、角鲨烯、4H-吡喃-4-酮、2,3-二氢-3,5-二羟基-6-甲基-、角鲨烯、4H-吡喃-4-酮、2,3-二氢-3,5-二羟基-6-甲基-、5-羟甲基糠醛、羽扇豆醇、十二烷酸、维生素E(α-生育酚)、新植二烯、叶绿醇和许多其他化合物。这些化合物具有抗菌、抗癌和药用特性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f48e/11681831/68481f287c7e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f48e/11681831/6d4bdc98ae17/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f48e/11681831/9456e3b75ca3/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f48e/11681831/6ecc2fab0647/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f48e/11681831/68481f287c7e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f48e/11681831/6d4bdc98ae17/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f48e/11681831/9456e3b75ca3/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f48e/11681831/6ecc2fab0647/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f48e/11681831/68481f287c7e/gr2.jpg

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