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自体脂肪移植隆鼻术后皮肤坏死:一例病例报告及文献复习

Skin necrosis after autologous fat grafting for augmentation rhinoplasty: a case report and review of the literature.

作者信息

Jiang Xiao, Cao Hanchen, He Xingfeng, Zou Xinhui, Mao Haoran, Tang Lingzhi, Lu Jinqiang

机构信息

Department of Plastic Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, P.R. China.

Innovative Technology Research Institute of Tissue Repair and Regeneration, Key Laboratory of Regenerative Medicine, Ministry of Education, Guangzhou, Guangdong Province, P.R. China.

出版信息

J Cosmet Laser Ther. 2024 Nov 16;26(5-8):138-142. doi: 10.1080/14764172.2024.2421013. Epub 2024 Dec 31.

DOI:10.1080/14764172.2024.2421013
PMID:39740095
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11750145/
Abstract

BACKGROUND

Autologous fat transplantation has gained increasing attention in the field of cosmetic surgery. However, a series of complications can occur after fat transplantation.

CASE PRESENTATION

A 24-year-old woman presented at our Hospital with nasal skin necrosis and ulceration. She had undergone autologous fat transplantation on the nose six days ago. Physical examination showed an abnormal skin range of approximately 5 × 2 cm on the left side of the nose. The initial diagnosis was "skin necrosis after autologous fat grafting for augmentation rhinoplasty." In addition to the conventional treatment, topical oxygen therapy (TOT) and platelet-rich fibrin (PRF) injection were applied to the nasal wounds area. After 16 days, the pale and dark areas of necrosis on nose were scabby, and the local skin conditions were significantly improved.

CONCLUSION

We treated a case of ischemic necrosis of the skin after autologous fat grafting for augmentation rhinoplasty. For this kind of local vascular embolism, we first proposed a comprehensive therapy of "biological + physical + drug." The therapeutic method achieved satisfactory results, providing a new strategy for the clinical treatment of vascular embolism.

摘要

背景

自体脂肪移植在整形手术领域越来越受到关注。然而,脂肪移植后可能会出现一系列并发症。

病例介绍

一名24岁女性因鼻皮肤坏死和溃疡前来我院就诊。她在六天前接受了鼻部自体脂肪移植。体格检查显示鼻子左侧皮肤异常范围约为5×2厘米。初步诊断为“隆鼻自体脂肪移植术后皮肤坏死”。除常规治疗外,对鼻部伤口区域采用局部氧疗(TOT)和富血小板纤维蛋白(PRF)注射。16天后,鼻子上坏死的苍白和深色区域结痂,局部皮肤状况明显改善。

结论

我们治疗了一例隆鼻自体脂肪移植术后皮肤缺血性坏死病例。对于这种局部血管栓塞,我们首次提出了“生物+物理+药物”的综合治疗方法。该治疗方法取得了满意的效果,为血管栓塞的临床治疗提供了新策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c8b/11750145/40a2ca458a3b/IJCL_A_2421013_F0003_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c8b/11750145/4847e8b01c42/IJCL_A_2421013_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c8b/11750145/1f74ad5e6a20/IJCL_A_2421013_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c8b/11750145/40a2ca458a3b/IJCL_A_2421013_F0003_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c8b/11750145/4847e8b01c42/IJCL_A_2421013_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c8b/11750145/1f74ad5e6a20/IJCL_A_2421013_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c8b/11750145/40a2ca458a3b/IJCL_A_2421013_F0003_OC.jpg

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Aesthet Surg J. 2021 Oct 15;41(11):NP1557-NP1570. doi: 10.1093/asj/sjab033.
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Severe Vascular Complications Caused by Facial Autologous Fat Grafting: A Critical Review.面部自体脂肪移植引起的严重血管并发症:一项批判性综述。
Ann Plast Surg. 2021 Mar 1;86(3S Suppl 2):S208-S219. doi: 10.1097/SAP.0000000000002691.
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Fat Grafting for Facial Rejuvenation Using Stromal Vascular Fraction Gel Injection.
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Clin Plast Surg. 2020 Jan;47(1):73-79. doi: 10.1016/j.cps.2019.09.001. Epub 2019 Oct 28.
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The Successful Mechanical Lipectomy Treatment of Cerebral Fat Embolism following Autologous Fat Injection.自体脂肪注射后脑脂肪栓塞的成功机械性脂肪清除术治疗
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