Son Seungmin, An Chung Sun, Yoon Weon-Jong, Jeong Yujeong, Han Sang-Chul, Kim Yun Beom, Lee Jong-Du, Oh Eugene, Choi Hwon, Kwon Miye, Kim Seongwook, Aziz Israr, Jung Man-Young, Im Jong Hee
School of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul, 08826, Republic of Korea; National Institute of Agricultural Sciences, Rural Development Administration, Jeonju, 54874, Republic of Korea.
School of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul, 08826, Republic of Korea.
Biochem Biophys Res Commun. 2025 Jan;745:151170. doi: 10.1016/j.bbrc.2024.151170. Epub 2024 Dec 13.
Soybeans are a critical crop that provides both protein and oil. In response to environmental stresses, mitogen-activated protein kinases (MPKs) play a key role in transmitting stress signals to the nucleus to initiate stress-responsive actions. Drought stress reduces plant development and productivity but the specific MPK responsible for drought stress responses has not been previously identified. In this study, we demonstrate that GmMPK6, a soybean MPK, responds to drought stress and enhances drought tolerance. GmMPK6 is activated in drought conditions through post-translational modifications. Inhibition of GmMPK6 activity leads to reduced drought resistance and a decrease in GmRD19A expression. Additionally, GmMPK6 activation is modulated by calcium signaling, highlighting GmMPK6 as a positive regulator of drought stress resistance in soybean. This study presents the first report of an MPK conferring drought tolerance in soybean.
大豆是一种重要的作物，能提供蛋白质和油脂。在应对环境胁迫时，丝裂原活化蛋白激酶（MPK）在将胁迫信号传递至细胞核以启动胁迫响应行动中发挥关键作用。干旱胁迫会降低植物的生长发育和生产力，但此前尚未鉴定出负责干旱胁迫响应的特定MPK。在本研究中，我们证明了大豆MPK——GmMPK6对干旱胁迫作出响应并增强了耐旱性。GmMPK6在干旱条件下通过翻译后修饰被激活。抑制GmMPK6的活性会导致抗旱性降低以及GmRD19A表达减少。此外，GmMPK6的激活受钙信号调节，这突出了GmMPK6作为大豆干旱胁迫抗性正向调节因子的作用。本研究首次报道了一种赋予大豆耐旱性的MPK。
