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机器学习在传染病学中的应用:潜在的应用和局限性。

Machine learning in infectious diseases: potential applications and limitations.

机构信息

College of Pharmacy, Al Ain University, Abu Dhabi, United Arab Emirates.

AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi, United Arab Emirates.

出版信息

Ann Med. 2024 Dec;56(1):2362869. doi: 10.1080/07853890.2024.2362869. Epub 2024 Jun 10.

Abstract

Infectious diseases are a major threat for human and animal health worldwide. Artificial Intelligence (AI) combined algorithms including Machine Learning and Big Data analytics have emerged as a potential solution to analyse diverse datasets and face challenges posed by infectious diseases. In this commentary we explore the potential applications and limitations of ML to management of infectious disease. It explores challenges in key areas such as outbreak prediction, pathogen identification, drug discovery, and personalized medicine. We propose potential solutions to mitigate these hurdles and applications of ML to identify biomolecules for effective treatment and prevention of infectious diseases. In addition to use of ML for management of infectious diseases, potential applications are based on catastrophic evolution events for the identification of biomolecular targets to reduce risks for infectious diseases and vaccinomics for discovery and characterization of vaccine protective antigens using intelligent Big Data analytics techniques. These considerations set a foundation for developing effective strategies for managing infectious diseases in the future.

摘要

传染病是全球人类和动物健康的主要威胁。人工智能(AI)结合了机器学习和大数据分析等算法,已成为分析多样化数据集和应对传染病带来挑战的潜在解决方案。在本评论中,我们探讨了机器学习在传染病管理中的潜在应用和局限性。它探讨了在爆发预测、病原体识别、药物发现和个性化医学等关键领域面临的挑战。我们提出了潜在的解决方案来减轻这些障碍,并应用机器学习来识别有效的传染病治疗和预防的生物分子。除了将机器学习用于传染病管理之外,还可以基于灾难性进化事件来识别生物分子靶标,以降低传染病风险,以及利用智能大数据分析技术进行疫苗组学研究,以发现和描述疫苗保护性抗原。这些考虑为未来制定有效的传染病管理策略奠定了基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1844/11168216/58b392fbe84e/IANN_A_2362869_F0001_C.jpg

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