精神分裂症患者照料者疾病家庭负担与生活质量的典型相关分析：来自中国西南部欠发达多民族地区精神分裂症特异性队列的证据
Canonical correlation analysis of family burden of disease and quality of life in caregivers of people living with schizophrenia: evidence from Schizophrenia-specific cohort in the less-developed multi-ethnic region of Southwest China.
作者信息
Wang Ximei, Zhang Teng, Li Mingsong, Yang Bo, Wang Liming, Fu Chuanwen, Zhang Nishang, Li Zhengxu, Yang Ce, Zhao Zhimin, Meng Qiong, Feng Yuemei, Yin Jianzhong
机构信息
Yunnan Provincial Key Laboratory of Public Health and Biosafety & School of Public Health, Kunming Medical University, 1168# West Chunrong Road, Chenggong Zone, Kunming, 650500, China.
Baoshan College of Traditional Chinese Medicine, Longyang District, Baoshan City, 678000, Yunnan Province, China.
出版信息
BMC Psychiatry. 2025 Jan 2;25(1):1. doi: 10.1186/s12888-024-06458-9.
BACKGROUND
Health-related quality of life is a multi-dimensional concept that involves individual's perceived physical and mental health, social relationships, and environment. Family members are the primary caregivers of people living with schizophrenia in China, the quality of life of caregiver of people living with schizophrenia is generally poorer, which may indirectly affect the quality of life of the people with schizophrenia.
METHODS
We conducted a comprehensive survey on quality of life in caregivers of people living with schizophrenia based on the Schizophrenia-specific cohort in the Less-developed Multi-ethnic Region of Southwest China to validate the accessibility and effectiveness of the schizophrenia family care model at the family level, caregivers of people living with schizophrenia were selected as participants in Baoshan City, Yunnan Province from September 2022 to March 2023, quality of life, family burden of disease, sociodemographic and behavioral information of participants were collected.
RESULTS
Domain scores for physical, psychological, social relationships, and environment of quality of life were 13.50 ± 2.61, 12.67 ± 2.40, 13.64 ± 2.32, and 12.46 ± 1.76 respectively. In our study, we found that gender, age, education level, personal monthly income, history of smoking and alcohol consumption, subjective sleep quality, relation to the patient, degree of self-care and the number of relapses in patient all influence 1 to 4 domains of quality of life for caregivers, stratified analysis was conducted to minimize the effect of gender on the results, we still found that history of smoking could positively predict the score of psychological domain and history of alcohol consumption could positively predict the score of social relationships domain. Canonical correlation analysis showed that the 'impact on family interaction' in family burden of disease was most closely related to quality of life.
CONCLUSION
Building harmonious family relationships can help improve the quality of life for caregivers of People living with schizophrenia.
背景
健康相关生活质量是一个多维度概念，涉及个体对自身身心健康、社会关系及环境的感知。在中国，家庭成员是精神分裂症患者的主要照料者，精神分裂症患者照料者的生活质量普遍较差，这可能会间接影响精神分裂症患者的生活质量。
方法
基于中国西南部欠发达多民族地区的精神分裂症特定队列，我们对精神分裂症患者照料者的生活质量进行了全面调查，以验证家庭层面精神分裂症家庭照料模式的可及性和有效性。2022年9月至2023年3月，选取云南省保山市的精神分裂症患者照料者作为参与者，收集了参与者的生活质量、家庭疾病负担、社会人口学及行为信息。
结果
生活质量的身体、心理、社会关系和环境领域得分分别为13.50±2.61、12.67±2.40、13.64±2.32和12.46±1.76。在我们的研究中，我们发现性别、年龄、教育水平、个人月收入、吸烟和饮酒史、主观睡眠质量、与患者的关系、自我照料程度以及患者的复发次数均会影响照料者生活质量的1至4个领域。进行分层分析以尽量减少性别对结果的影响，我们仍然发现吸烟史可正向预测心理领域得分，饮酒史可正向预测社会关系领域得分。典型相关分析表明，家庭疾病负担中的“对家庭互动的影响”与生活质量关系最为密切。
结论
建立和谐的家庭关系有助于提高精神分裂症患者照料者的生活质量。
Zotero 插件