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一名10岁男孩的类癌肿瘤:诊断与管理挑战——一例罕见病例报告

Carcinoid tumor in a 10-year-old boy challenges in diagnosis and management: A rare case report.

作者信息

Shahoud Maya, Abdin Dania, Ismail Ahmad, Ismail Fatima, Azzawi Tameem

机构信息

University of Aleppo, Faculty of Medicine, Aleppo, Syria.

University of Aleppo, Faculty of Medicine, Aleppo, Syria.

出版信息

Int J Surg Case Rep. 2025 Jan;126:110811. doi: 10.1016/j.ijscr.2024.110811. Epub 2024 Dec 30.

Abstract

INTRODUCTION

Lung cancer is a major cause of cancer-related deaths, with 2 million new cases annually. Bronchopulmonary neuroendocrine tumors (BP-NETs) comprise about 20 % of lung cancers, including typical carcinoid tumors (TC). While tobacco is a primary risk factor, non-tobacco factors also play a role. Typically, NETs affect individuals over 50, with typical carcinoids being rare in children. This report discusses a unique case of a typical carcinoid in a 10-year-old boy linked to environmental exposure.

CASE PRESENTATION

A 10-year-old boy presented with cough, dyspnea, hemoptysis, and recurrent pneumonia. Imaging revealed lobar collapse and a large mass in the right lower lobe. Surgical excision confirmed a carcinoid tumor with no lymph node metastasis. Post-surgery, the patient showed complete symptom resolution during follow-up.

DISCUSSION

Neuroendocrine tumors (NETs) are uncommon in children and can present with respiratory symptoms. This case highlights the importance of considering NETs in pediatric patients, particularly with environmental exposure. Timely diagnosis and surgical intervention led to a successful outcome, emphasizing the need for awareness of these tumors in younger populations.

CONCLUSION

This case report presents a rare typical carcinoid tumor in a 10-year-old boy, with successful surgical resection leading to complete symptom resolution. It highlights the need to recognize bronchopulmonary neuroendocrine tumors in children, particularly those with environmental exposure, and underscores the importance of ongoing follow-up for affected patients.

摘要

引言

肺癌是癌症相关死亡的主要原因,每年有200万新发病例。支气管肺神经内分泌肿瘤(BP-NETs)约占肺癌的20%,包括典型类癌肿瘤(TC)。虽然烟草是主要危险因素,但非烟草因素也起作用。通常,神经内分泌肿瘤影响50岁以上的个体,典型类癌在儿童中罕见。本报告讨论了一例与环境暴露相关的10岁男孩患典型类癌的独特病例。

病例介绍

一名10岁男孩出现咳嗽、呼吸困难、咯血和反复肺炎。影像学检查显示肺叶萎陷和右下叶有一个大肿块。手术切除证实为类癌肿瘤,无淋巴结转移。术后,患者在随访期间症状完全缓解。

讨论

神经内分泌肿瘤(NETs)在儿童中并不常见,可表现为呼吸道症状。该病例强调了在儿科患者中考虑神经内分泌肿瘤的重要性,特别是有环境暴露史的患者。及时诊断和手术干预取得了成功,强调了在年轻人群中认识这些肿瘤的必要性。

结论

本病例报告介绍了一名10岁男孩罕见的典型类癌肿瘤,成功的手术切除导致症状完全缓解。它强调了在儿童中识别支气管肺神经内分泌肿瘤的必要性,特别是那些有环境暴露史的儿童,并强调了对受影响患者进行持续随访的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeb7/11755083/59c5b6343ec4/gr1.jpg

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