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酗酒者后代的轻微脑功能障碍与神经心理测试表现

Minimal brain dysfunction and neuropsychological test performance in offspring of alcoholics.

作者信息

Hesselbrock V M, Stabenau J R, Hesselbrock M N

出版信息

Recent Dev Alcohol. 1985;3:65-82. doi: 10.1007/978-1-4615-7715-7_6.

DOI:10.1007/978-1-4615-7715-7_6
PMID:3975458
Abstract

Previous studies have indicated that alcoholics report a high frequency of problem behaviors in childhood. Additionally, certain neuropsychological deficits are often evident. Both childhood problem behavior and antecedent neuropsychological deficits have been suggested as risk factors for the later development of alcoholism. However, neither set of variables nor their interrelationship have been previously investigated in a sample at high risk for the development of alcoholism. In this study, unaffected offspring of an alcoholic parent and unaffected offspring of nonalcoholic parents were examined. Although attention deficit disorder/hyperactivity and conduct disorder prior to age twelve predicted the onset of drinking, the frequency of childhood behaviors was similar in both groups. Further, the neuropsychological performances of the high-risk and low-risk samples were also similar and within normal limits. The theoretical and methodological implications of these findings for future research are discussed.

摘要

先前的研究表明,酗酒者报告童年期问题行为的频率很高。此外,某些神经心理缺陷往往很明显。童年期问题行为和先前的神经心理缺陷都被认为是酗酒后期发展的风险因素。然而,在酗酒发展高风险样本中,这两组变量及其相互关系此前均未得到研究。在本研究中,对酗酒父母的未受影响后代和非酗酒父母的未受影响后代进行了检查。尽管12岁之前的注意力缺陷多动障碍和品行障碍可预测饮酒的开始,但两组童年行为的频率相似。此外,高风险和低风险样本的神经心理表现也相似且在正常范围内。讨论了这些发现对未来研究的理论和方法学意义。

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