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炎症性肠病的住院患者营养考量

Inpatient Nutritional Considerations in Inflammatory Bowel Disease.

作者信息

Chirayath Subin, Bahirwani Janak, Pandey Akash, Memel Zoe, Park Sunhee, Schneider Yecheskel

机构信息

St Luke's University Hospital, Fountain Hill, USA.

Pediatric Gastroenterology, Orlando Health Arnold Palmer Hospital for Children, Orlando, FL, USA.

出版信息

Curr Gastroenterol Rep. 2025 Dec;27(1):9. doi: 10.1007/s11894-024-00958-0. Epub 2025 Jan 6.

DOI:10.1007/s11894-024-00958-0
PMID:39760825
Abstract

PURPOSE OF REVIEW

This review aims to explain the causes, diagnosis, and treatment of malnutrition in hospitalized patients with inflammatory bowel disease (IBD), focusing on both adults and children.

RECENT FINDINGS

Malnutrition is common among IBD patients, affecting up to 85% of individuals, and is linked to higher rates of illness, death, and longer hospital stays. Recent studies highlight the importance of early detection using tools like the Subjective Global Assessment (SGA) and handgrip strength tests. Nutritional interventions-such as exclusive enteral nutrition (EEN) and parenteral nutrition (PN)-have proven effective in inducing remission and improving patient outcomes, especially in pediatric Crohn's disease. New evidence suggests that optimizing nutrition before and after surgery, as well as using immunonutrition, may reduce postoperative complications. Early identification and management of malnutrition in hospitalized IBD patients may be important for improving clinical outcomes. Using appropriate nutritional screening tools and creating personalized nutrition plans can help with recovery, decrease hospital stays, and improve quality of life. Further research is needed to develop standard protocols for nutritional assessment and treatment in this patient population.

摘要

综述目的

本综述旨在解释炎症性肠病(IBD)住院患者营养不良的病因、诊断和治疗,重点关注成人和儿童。

最新研究结果

营养不良在IBD患者中很常见,高达85%的患者受其影响,且与更高的发病率、死亡率以及更长的住院时间相关。近期研究强调了使用主观全面评定法(SGA)和握力测试等工具进行早期检测的重要性。营养干预措施,如全肠内营养(EEN)和肠外营养(PN),已被证明在诱导缓解和改善患者预后方面有效,尤其是在儿童克罗恩病中。新证据表明,优化手术前后的营养状况以及使用免疫营养,可能会减少术后并发症。早期识别和管理IBD住院患者的营养不良对于改善临床结局可能很重要。使用适当的营养筛查工具并制定个性化营养计划有助于康复、缩短住院时间并提高生活质量。需要进一步研究来制定针对该患者群体的营养评估和治疗标准方案。

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本文引用的文献

1
AGA Clinical Practice Update on Diet and Nutritional Therapies in Patients With Inflammatory Bowel Disease: Expert Review.AGA 临床实践更新:炎症性肠病患者的饮食和营养治疗:专家综述。
Gastroenterology. 2024 Mar;166(3):521-532. doi: 10.1053/j.gastro.2023.11.303. Epub 2024 Jan 23.
2
The Crohn's Disease Exclusion Diet: A Comprehensive Review of Evidence, Implementation Strategies, Practical Guidance, and Future Directions.克罗恩病排除饮食:证据、实施策略、实用指南的全面综述及未来方向。
Inflamm Bowel Dis. 2024 Oct 3;30(10):1888-1902. doi: 10.1093/ibd/izad255.
3
Use of oral diet and nutrition support in management of stricturing and fistulizing Crohn's disease.
口服饮食和营养支持在狭窄和瘘管性克罗恩病治疗中的应用。
Nutr Clin Pract. 2023 Dec;38(6):1282-1295. doi: 10.1002/ncp.11068. Epub 2023 Sep 4.
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ESPEN guideline on Clinical Nutrition in inflammatory bowel disease.欧洲临床营养与代谢学会(ESPEN)炎症性肠病临床营养指南
Clin Nutr. 2023 Mar;42(3):352-379. doi: 10.1016/j.clnu.2022.12.004. Epub 2023 Jan 13.
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Evaluation of Nutritional Characteristics Reveals Similar Prevalence of Malnutrition in Patients with Ulcerative Colitis and Crohn's Disease.营养特征评估显示,溃疡性结肠炎和克罗恩病患者营养不良的患病率相似。
Dig Dis Sci. 2023 Feb;68(2):580-595. doi: 10.1007/s10620-022-07652-z. Epub 2022 Sep 5.
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High Prevalence of Malnutrition and Micronutrient Deficiencies in Patients With Inflammatory Bowel Disease Early in Disease Course.炎症性肠病患者在疾病早期存在较高的营养不良和微量营养素缺乏发生率。
Inflamm Bowel Dis. 2023 Mar 1;29(3):423-429. doi: 10.1093/ibd/izac102.
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Nutrition in Patients with Inflammatory Bowel Diseases: A Narrative Review.炎症性肠病患者的营养治疗:叙述性综述。
Nutrients. 2022 Feb 10;14(4):751. doi: 10.3390/nu14040751.
8
Sarcopenia Is More Prevalent Among Inflammatory Bowel Disease Patients Undergoing Surgery and Predicts Progression to Surgery Among Medically Treated Patients.肌肉减少症在接受手术的炎症性肠病患者中更为普遍,并可预测接受药物治疗的患者是否会进展为需要手术治疗。
Inflamm Bowel Dis. 2022 Dec 1;28(12):1844-1850. doi: 10.1093/ibd/izac013.
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The Crohn's disease exclusion diet for induction and maintenance of remission in adults with mild-to-moderate Crohn's disease (CDED-AD): an open-label, pilot, randomised trial.成人轻至中度克罗恩病缓解诱导和维持的克罗恩病排除饮食(CDED-AD):一项开放标签、先导性随机试验。
Lancet Gastroenterol Hepatol. 2022 Jan;7(1):49-59. doi: 10.1016/S2468-1253(21)00299-5. Epub 2021 Nov 2.
10
Optimizing Inpatient Nutrition Care of Adult Patients with Inflammatory Bowel Disease in the 21st Century.优化 21 世纪炎症性肠病成年患者的住院营养护理
Nutrients. 2021 May 9;13(5):1581. doi: 10.3390/nu13051581.