Suppr超能文献

全身冷刺激对调节成人脑瘫患者的痉挛是否有效?一项案例研究。

Is Whole-Body Cryostimulation Useful in Modulating Spasticity in Adults with Cerebral Palsy? A Case Study.

作者信息

Piterà Paolo, Bigoni Matteo, Prina Elisa, Barrera Boris, Yavuz Duru Ceren, Verme Federica, Fontana Jacopo Maria, Priano Lorenzo, Mauro Alessandro, Capodaglio Paolo

机构信息

Department of Neurosciences "Rita Levi Montalcini", University of Turin, 10126 Turin, Italy.

Laboratory of Clinical Neurobiology, IRCCS Istituto Auxologico Italiano, San Giuseppe Hospital, 28824 Verbania, Italy.

出版信息

J Clin Med. 2024 Dec 16;13(24):7674. doi: 10.3390/jcm13247674.

Abstract

: This case study investigates the effect of a five-session whole-body cryostimulation (WBC) cycle on a 55-year-old female patient with cerebral palsy (CP) and lower limb spasticity (LLS) with a typical diplegic gait pattern. CP is a common physical disability characterized by motor impairments, including spasticity, which significantly impacts mobility and quality of life. The current treatments for spasticity often have limited efficacy and considerable side effects, making alternative therapies like WBC an area of interest. : The patient underwent a 10-day inpatient rehabilitation program integrated with five WBC sessions at -110 °C for 2 min. The treatment effects were assessed immediately before and after the five WBC sessions using the Ashworth Scale, Fugl-Meyer Assessment, H-reflex test, and gait analysis. Psychosocial outcomes were measured with the SF-36, WHO-5, PSQI, ESS, and BDI questionnaires. Immediately after the WBC cycle, gait analysis showed increased walking speed (0.48 to 0.61 m/s left; 0.49 to 0.57 m/s right) and step length (0.30 to 0.38 m left; 0.30 to 0.35 m right). The H/M ratio in the H-reflex test improved, indicating a better neuromuscular efficiency. Psychosocial assessments revealed a 42.5% reduction in pain and a 24% improvement in overall quality of life and well-being. : The objective improvements in gait parameters and neuromuscular modulation, along with the subjectively reported enhancements in functional abilities, highlight the potential of WBC as a valuable addition to rehabilitation strategies for this population. Further research is needed to confirm these findings and assess long-term outcomes.

摘要

本案例研究调查了为期五节的全身冷冻刺激(WBC)疗程对一名55岁患有脑瘫(CP)和下肢痉挛(LLS)且具有典型双侧瘫步态模式的女性患者的影响。脑瘫是一种常见的身体残疾,其特征为运动障碍,包括痉挛,这对行动能力和生活质量有显著影响。目前针对痉挛的治疗方法往往疗效有限且副作用较大,使得像全身冷冻刺激这样的替代疗法成为一个受关注的领域。

该患者接受了一个为期10天的住院康复计划,其中包括在-110°C下进行五节每次2分钟的全身冷冻刺激疗程。在五节全身冷冻刺激疗程前后,使用Ashworth量表、Fugl-Meyer评估、H反射测试和步态分析对治疗效果进行了评估。使用SF-36、WHO-5、PSQI、ESS和BDI问卷对心理社会结果进行了测量。在全身冷冻刺激疗程结束后,步态分析显示步行速度增加(左侧从0.48米/秒增至0.61米/秒;右侧从0.49米/秒增至0.57米/秒),步长增加(左侧从0.30米增至0.38米;右侧从0.30米增至0.35米)。H反射测试中的H/M比值有所改善,表明神经肌肉效率提高。心理社会评估显示疼痛减轻了42.5%,整体生活质量和幸福感提高了24%。

步态参数和神经肌肉调节方面的客观改善,以及主观报告的功能能力增强,凸显了全身冷冻刺激作为该人群康复策略中一项有价值补充的潜力。需要进一步的研究来证实这些发现并评估长期结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/962c/11677623/32abcd7f5798/jcm-13-07674-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验