Pan Lan, Zhou Tianyuan, Chen Chen, Xu Haiyan, Wang Wenli
College of Traditional Chinese Medicine, Xinjiang Medical University, Urumqi 830017, China.
Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Molecules. 2024 Dec 12;29(24):5876. doi: 10.3390/molecules29245876.
L., a species within the genus, is broadly distributed across Southern Europe and Central Asia. In China, its berries, branches, and leaves are traditionally employed in Uyghur medicine to address conditions such as rheumatoid arthritis, itchy skin, tinnitus, deafness, and urinary discomfort. Notably, the plant's primary bioactive constituents are terpenoids, lignans, and flavonoids. Contemporary pharmacological studies have revealed that exhibits a range of bioactivities, including insecticidal, antimicrobial, antioxidant, anti-inflammatory, and antitumor effects. These diverse therapeutic properties can be attributed to its rich chemical profile, which comprises 279 distinct compounds such as terpenoids, lignans, flavonoids, coumarins, and others, isolated to date. This comprehensive review systematically organizes and summarizes the botanical characteristics, traditional uses, chemical composition, pharmacological activities, toxicity, limitations, and future prospects of . It aims to offer a valuable scientific reference and fresh perspectives for further research, development, and application of this plant.
L.是该属中的一个物种，广泛分布于南欧和中亚。在中国，其浆果、树枝和叶子在维吾尔医学中传统上用于治疗类风湿性关节炎、皮肤瘙痒、耳鸣、耳聋和泌尿不适等病症。值得注意的是，该植物的主要生物活性成分是萜类化合物、木脂素和黄酮类化合物。当代药理学研究表明，其具有一系列生物活性，包括杀虫、抗菌、抗氧化、抗炎和抗肿瘤作用。这些多样的治疗特性可归因于其丰富的化学组成，迄今为止已分离出279种不同的化合物，如萜类化合物、木脂素、黄酮类化合物、香豆素等。这篇综述系统地整理和总结了L.的植物学特征、传统用途、化学成分、药理活性、毒性、局限性和未来前景。旨在为该植物的进一步研究、开发和应用提供有价值的科学参考和新的视角。
