Grassia Giulia, Amisano Francesco, Gaiarsa Stefano, Bagnarino Jessica, Compagno Francesca, Panigari Arianna, Baldanti Fausto, Monzillo Vincenzina, Barbarini Daniela
Department of Microbiology & Virology, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Specialization School of Microbiology and Virology, University of Pavia, 27100 Pavia, Italy.
Microorganisms. 2024 Nov 26;12(12):2431. doi: 10.3390/microorganisms12122431.
is a Non-Tuberculous Mycobacterium (NTM) belonging to the group, often associated with veterinary diseases, such as bovine farcy. However, it can also cause human infections and appears to be involved in Catheter-Associated Infections in immunocompromised patients. Here, we report the first Italian isolation of a strain of from a 16-year-old oncological female patient being treated at Fondazione IRCCS Policlinico San Matteo Pavia (Italy). Following pain at the Port-a-Cath site, a pus culture was collected and the positivity for the group revealed the NTM infection. Antimicrobial susceptibility tests were performed and interpreted according to the available CLSI breakpoints. This information allowed us to implement the correct antibiotic therapy that, together with the device removal, led to the patient's recovery. Finally, due to the increasing number of isolations, the possible presence of NTM infections in prosthetic devices should be among the primary diagnostic questions in a clinical setting.
是一种属于该组的非结核分枝杆菌（NTM），常与兽医疾病相关，如牛皮肤鼻疽。然而，它也可引起人类感染，并且似乎与免疫功能低下患者的导管相关感染有关。在此，我们报告在意大利首次从一名在意大利帕维亚圣马泰奥综合医院IRCCS基金会接受治疗的16岁肿瘤女性患者中分离出一株该菌。在输液港部位出现疼痛后，采集了脓液培养物，该组的阳性结果显示存在NTM感染。根据现有的CLSI折点进行了抗菌药敏试验并进行了解释。这些信息使我们能够实施正确的抗生素治疗，该治疗与移除装置一起使患者康复。最后，由于分离株数量的增加，在临床环境中，假体装置中可能存在NTM感染应作为主要诊断问题之一。
