模拟如何阐明Nav1.5通道阻滞剂的作用机制？
How could simulations elucidate Nav1.5 channel blockers mechanism?
作者信息
Pipatpolkai Tanadet
机构信息
Division of Physics and Applied Physics, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, Singapore.
出版信息
J Gen Physiol. 2025 Mar 3;157(2). doi: 10.1085/jgp.202413730. Epub 2025 Jan 7.
Abstract
Tao and Corry used metadynamics, an enhanced sampling method to identify and classify Nav channel blockers.
摘要
陶和科里使用了元动力学，一种用于识别和分类钠通道阻滞剂的增强采样方法。
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