Suppr超能文献

研究加拿大娱乐用大麻合法化前后,患有严重并发精神健康和物质使用障碍的精神病患者中,大麻使用与情绪、焦虑及精神病症状之间的关系。

Examining the Relationship Between Cannabis Use and Mood, Anxiety, and Psychotic Symptoms in Psychiatric Patients with Severe Concurrent Mental Health and Substance Use Disorders Before and After Recreational Cannabis Legalization in Canada.

作者信息

Thiessen Karina A, Schütz Christian G

机构信息

Department of Psychiatry, Faculty of Medicine, University of British Columbia.

Djavad Mowafaghian Centre for Brain Health, Faculty of Medicine, University of British Columbia.

出版信息

Cannabis. 2024 Dec 12;7(3):90-105. doi: 10.26828/cannabis/2024/000258. eCollection 2024.

Abstract

OBJECTIVE

The relationship between cannabis use and mental health has garnered significant attention in recent decades. However, studies have largely been in general populations or in countries in which recreational cannabis use is illegal.

METHOD

The current cross-sectional study examines the relationship between cannabis use, mood disorders, anxiety, and psychosis in an inpatient psychiatric population with severe concurrent mental health and substance use disorders, exploring the potential moderating effect of the legalization of recreational cannabis in Canada.

RESULTS

Cannabis use compared to non-use was associated with higher self-reported depression, anxiety, and psychotic symptoms but was not associated with diagnosis of a mood, anxiety, or psychotic disorder. Frequency of cannabis use was unrelated to mental health outcomes, but age of first use was negatively associated with self-reported psychoticism symptoms. There were some significant associations between recreational cannabis legalization and mental health, but legalization was largely unrelated to outcomes. There were also some significant differences by demographics.

CONCLUSIONS

While findings are relatively consistent with prior literature, some significant associations differed, suggesting the importance of examining concurrent disorder patients as a unique population when examining relationships between cannabis use and mental health.

摘要

目的

近几十年来,大麻使用与心理健康之间的关系备受关注。然而,相关研究主要针对普通人群或娱乐性大麻使用违法的国家。

方法

当前的横断面研究考察了患有严重并发心理健康和物质使用障碍的住院精神科患者中大麻使用、情绪障碍、焦虑和精神病之间的关系,探讨了加拿大娱乐性大麻合法化的潜在调节作用。

结果

与未使用大麻相比,使用大麻与更高的自我报告的抑郁、焦虑和精神病症状相关,但与情绪、焦虑或精神病性障碍的诊断无关。大麻使用频率与心理健康结果无关,但首次使用大麻的年龄与自我报告的精神病性症状呈负相关。娱乐性大麻合法化与心理健康之间存在一些显著关联,但合法化在很大程度上与结果无关。在人口统计学方面也存在一些显著差异。

结论

虽然研究结果与先前的文献相对一致,但一些显著关联有所不同,这表明在研究大麻使用与心理健康之间的关系时,将并发疾病患者作为一个独特群体进行考察具有重要意义。

相似文献

2
[Impact of the legalization of recreational cannabis on the risk of psychosis: A systematic review of the literature].
Encephale. 2025 Apr;51(2):186-201. doi: 10.1016/j.encep.2024.05.003. Epub 2024 Sep 6.
5
Legalization of cannabis use in Canada: Impacts on the cannabis use profiles of youth seeking services for substance use.
J Subst Abuse Treat. 2021 Jul;126:108340. doi: 10.1016/j.jsat.2021.108340. Epub 2021 Feb 25.
7
Effects of Recreational Cannabis Legalization on Mental Health: Scoping Review.
Psychiatr Serv. 2024 Sep 1;75(9):872-887. doi: 10.1176/appi.ps.20230434. Epub 2024 Apr 23.

本文引用的文献

3
The implementation and public health impacts of cannabis legalization in Canada: a systematic review.
Addiction. 2023 Nov;118(11):2062-2072. doi: 10.1111/add.16274. Epub 2023 Jun 28.
4
Age, Period, and Cohort Trends in Perceived Mental Health Treatment Need and Differences by Mental Health Severity in the United States, 2008-2019.
Community Ment Health J. 2023 May;59(4):631-640. doi: 10.1007/s10597-022-01044-3. Epub 2022 Oct 28.
6
Cannabinoids: Therapeutic Use in Clinical Practice.
Int J Mol Sci. 2022 Mar 19;23(6):3344. doi: 10.3390/ijms23063344.
9
Role of Cannabidiol in the Therapeutic Intervention for Substance Use Disorders.
Front Pharmacol. 2021 May 20;12:626010. doi: 10.3389/fphar.2021.626010. eCollection 2021.
10
Cannabis and mental health: Prevalence of use and modes of cannabis administration by mental health status.
Addict Behav. 2021 Oct;121:106991. doi: 10.1016/j.addbeh.2021.106991. Epub 2021 May 19.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验