A Pilot Report on Extracting Symptom Onset Date and Time from Clinical Notes in Patients Presenting with Chest Pain.

Acute coronary syndrome (ACS) is an acute heart disease that often evolves rapidly. In ACS patients presenting with no-ST-segment elevation (NSTE-ACS), the timing of symptom onset pre-hospital may inform the disease stage and prognosis. We pilot-tested two off-the-shelf natural language processing (NLP) pipelines, namely and (), to extract date and time (DateTime) information of patient-reported chest pain symptoms from electronic health records (EHR) clinical notes. We included three types of clinical notes (N=71): History and Physical (n=49), Emergency Department Screening (n=3), and Triage Notes (n=19). All notes were manually annotated for the true DateTime of symptom onset. returned matching DateTime outputs in 36 notes (50.7%), while returned zero matched outputs. performed better than , although it was still suboptimal. Both pipelines require constant refinement and custom improvements. Methods for a large-scale, automated DateTime extraction from EHR clinical notes further investigation.