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用于生物医学成像与传感的光学超表面

Optical Metasurfaces for Biomedical Imaging and Sensing.

作者信息

Kim Hongyoon, Yun Heechang, Jeong Sebin, Lee Seokho, Cho Eunseo, Rho Junsuk

机构信息

Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea.

Department of Chemical Engineering, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea.

出版信息

ACS Nano. 2025 Jan 28;19(3):3085-3114. doi: 10.1021/acsnano.4c14751. Epub 2025 Jan 13.

DOI:10.1021/acsnano.4c14751
PMID:39805079
Abstract

Optical metasurfaces, arrays of nanostructures engineered to manipulate light, have emerged as a transformative technology in both research and industry due to their compact design and exceptional light control capabilities. Their strong light-matter interactions enable precise wavefront modulation, polarization control, and significant near-field enhancements. These unique properties have recently driven their application in biomedical fields. In particular, metasurfaces have led to breakthroughs in biomedical imaging technologies, such as achromatic imaging, phase imaging, and extended depth-of-focus imaging. They have also advanced cutting-edge biosensing technologies, featuring high-quality factor resonators and near-field enhancements. As the demand for device miniaturization and system integration increases, metasurfaces are expected to play a pivotal role in the development of next-generation biomedical devices. In this review, we explore the latest advancements in the use of metasurfaces for biomedical applications, with a particular focus on imaging and sensing. Additionally, we discuss future directions aimed at transforming the biomedical field by leveraging the full potential of metasurfaces to provide compact, high-performance solutions for a wide range of applications.

摘要

光学超表面是经过设计用于操控光的纳米结构阵列,由于其紧凑的设计和卓越的光控制能力,已成为研究和工业领域的变革性技术。它们强大的光与物质相互作用能够实现精确的波前调制、偏振控制以及显著的近场增强。这些独特特性最近推动了它们在生物医学领域的应用。特别是,超表面已在生物医学成像技术方面取得突破,如消色差成像、相位成像和扩展焦深成像。它们还推动了前沿生物传感技术的发展,其特点是具有高品质因数谐振器和近场增强。随着对设备小型化和系统集成需求的增加,超表面有望在下一代生物医学设备的开发中发挥关键作用。在本综述中,我们探讨了超表面在生物医学应用方面的最新进展,特别关注成像和传感。此外,我们还讨论了旨在通过充分利用超表面的潜力来变革生物医学领域的未来方向,以便为广泛应用提供紧凑、高性能的解决方案。

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