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[具体物质名称]的全成分提取物及其对表皮再生的影响。 （你提供的原文中“of”后面缺少具体物质名称）

Full-component extract of and its effect on epidermal regeneration.

作者信息

Huang Hongbin, Qian Jin, Zeng Lanlan, Zhang Jin, Peng Xiaobo, Tang Xilong, Tang Yanzhang, Fu Meimei, Liu Qi, Song Fengrui, Guo Jinshan, Lu Zhihui

机构信息

Guangzhou Cadlin Cosmetics Technology Co., Ltd. No. 2 Fengxiang South Road, Jianggao, Baiyun District Guangzhou 510450 P. R. China.

Regenerative Medicine and Tissue Repair Material Research Center, HuangpuInstitute of Materials 88 Yonglong Avenue of Xinlong Town Guangzhou 511363 P. R. China.

出版信息

RSC Adv. 2025 Jan 20;15(3):1713-1720. doi: 10.1039/d4ra04301d. eCollection 2025 Jan 16.

DOI:10.1039/d4ra04301d
PMID:39835209
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11744354/
Abstract

As a well-known aromatic herb rich in various bioactive molecules, the extract of is widely used in cosmetics. However, the extraction process for is far from perfect. Moreover, the water- and oil-soluble components are too complex to be compatible with each other. Thus, the traditional water- or oil-based extracts of encompass only water- or oil-soluble components, respectively. The effective components being incomplete results in significantly reduced effects. Therefore, obtaining a full-component extract of is imperative to ensure its full functionality. Herein, a full-component extract of based on miscibility between polyol and oil was developed by extracting water-soluble active substances with a ternary solvent, followed by mixing them with oil extracts of . In ternary solvents, most water-soluble compounds of can be extracted by ethanol. During evaporation, the water-soluble components are transferred and dissolved in hexanediol from the solvent. Thus, by blending hexanediol with caprylic/capric triglyceride (GTCC), we successfully created a potent full-component extract of . Through the study of the barrier-weakening 3D full-skin model, it was found that the full-component extract of , rich in chlorogenic acid, could significantly promote the epidermal regeneration of UV-induced skin damage compared to the oil-based extract components.

摘要

作为一种富含多种生物活性分子的著名芳香草本植物，[植物名称]的提取物被广泛应用于化妆品中。然而，[植物名称]的提取工艺远非完美。此外，其水溶性和油溶性成分过于复杂，难以相互兼容。因此，传统的水基或油基[植物名称]提取物分别只包含水溶性或油溶性成分。有效成分不完整导致效果显著降低。因此，获得[植物名称]的全成分提取物对于确保其全部功能至关重要。在此，通过用三元溶剂提取水溶性活性物质，然后将它们与[植物名称]的油提取物混合，开发了一种基于多元醇与油的混溶性的[植物名称]全成分提取物。在三元溶剂中，[植物名称]的大多数水溶性化合物可被乙醇提取。在蒸发过程中，水溶性成分从溶剂转移并溶解在己二醇中。因此，通过将己二醇与辛酸/癸酸甘油三酯（GTCC）混合，我们成功制备了一种有效的[植物名称]全成分提取物。通过对屏障减弱3D全皮肤模型的研究发现，与油基提取物成分相比，富含绿原酸的[植物名称]全成分提取物能显著促进紫外线诱导的皮肤损伤的表皮再生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6432/11744354/19aae2c0060d/d4ra04301d-f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6432/11744354/a72487b5670e/d4ra04301d-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6432/11744354/26a09883c463/d4ra04301d-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6432/11744354/61547328840b/d4ra04301d-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6432/11744354/6136edaa2331/d4ra04301d-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6432/11744354/d1080c57176c/d4ra04301d-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6432/11744354/9569fe0dd17e/d4ra04301d-f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6432/11744354/cad16089f232/d4ra04301d-f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6432/11744354/19aae2c0060d/d4ra04301d-f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6432/11744354/a72487b5670e/d4ra04301d-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6432/11744354/26a09883c463/d4ra04301d-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6432/11744354/61547328840b/d4ra04301d-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6432/11744354/6136edaa2331/d4ra04301d-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6432/11744354/d1080c57176c/d4ra04301d-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6432/11744354/9569fe0dd17e/d4ra04301d-f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6432/11744354/cad16089f232/d4ra04301d-f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6432/11744354/19aae2c0060d/d4ra04301d-f8.jpg

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