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595纳米脉冲染料激光治疗越南患者血管瘤的疗效

Efficacy of the 595 nm pulsed dye laser in the treatment of hemangiomas in Vietnamese patients.

作者信息

Hải Lê Thị Thu, Phương Bùi Thị Thu, Minh Phạm Ngọc, Firas Al-Niaimi

机构信息

108 Central Military Hospital, Hanoi, Vietnam.

Aalborg University Hospital, Aalborg, Denmark.

出版信息

Lasers Med Sci. 2025 Jan 24;40(1):41. doi: 10.1007/s10103-024-04230-9.

DOI:10.1007/s10103-024-04230-9
PMID:39853410
Abstract

Hemangiomas are common benign vascular tumors that often present in childhood. The 595 nm pulsed dye laser (PDL) is now being widely used to treat vascular skin lesions. This case series was performed to review the therapeutic efficacy and safety of PDL in the treatment of hemangiomas among Vietnamese patients. A total of 43 Vietnamese patients (79.1% females), mean age was 8.83 years old (2 months - 54 years old), with a clinical diagnosis of hemangioma, were treated with the PDL over 2 years. Treatments were performed every 4 weeks. Hemangioma lesions that occur on the head and the neck are seen in 65.1%, 67.4% of superficial, and 32.6% of mixed hemangioma subtypes. The mean treatment is 5.3 times. Excellent-good results were achieved in 86.1%, average results in 11.6%. No permanent side effects during the treatments were observed. Treatment of hemangiomas using the 595 nm PDL is an effective and safe method in the skin types of Vietnamese patients. The effect does require several treatment sessions.

摘要

血管瘤是常见的良性血管肿瘤,常在儿童期出现。595纳米脉冲染料激光(PDL)目前被广泛用于治疗皮肤血管病变。本病例系列旨在回顾PDL治疗越南患者血管瘤的疗效和安全性。在两年多的时间里,共有43例临床诊断为血管瘤的越南患者(79.1%为女性)接受了PDL治疗,平均年龄为8.83岁(2个月至54岁)。治疗每4周进行一次。65.1%的血管瘤病变发生在头颈部,浅表型血管瘤占67.4%,混合型血管瘤占32.6%。平均治疗次数为5.3次。86.1%的患者取得了优-良效果,11.6%的患者效果一般。治疗期间未观察到永久性副作用。对于越南患者的皮肤类型,使用595纳米PDL治疗血管瘤是一种有效且安全的方法。不过该效果确实需要多次治疗。

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本文引用的文献

1
Risk Factors for Degree and Type of Sequelae After Involution of Untreated Hemangiomas of Infancy.婴儿期未治疗的血管瘤消退后后遗症的程度和类型的危险因素。
JAMA Dermatol. 2016 Nov 1;152(11):1239-1243. doi: 10.1001/jamadermatol.2016.2905.
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Treatment of infantile haemangiomas: recommendations of a European expert group.婴儿血管瘤的治疗:欧洲专家组的建议
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Effect of early long-pulse pulsed dye laser treatment in infantile hemangiomas.早期长脉宽脉冲染料激光治疗婴儿血管瘤的疗效。
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Infantile hemangiomas: A review.婴儿血管瘤:综述
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Clinical efficacy of the 595 nm pulsed dye laser in the treatment of childhood superficial hemangioma - analysis of 10-year application in Chinese patients.595纳米脉冲染料激光治疗儿童浅表性血管瘤的临床疗效——对中国患者10年应用情况的分析
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Superficial hemangioma: pulsed dye laser versus wait-and-see.表浅型血管瘤:脉冲染料激光与等待观察的比较。
Dermatol Surg. 2013 Mar;39(3 Pt 1):414-21. doi: 10.1111/dsu.12081. Epub 2012 Dec 26.
7
Untreated hemangiomas: growth pattern and residual lesions.未治疗的血管瘤:生长模式和残留病变。
Plast Reconstr Surg. 2011 Apr;127(4):1643-1648. doi: 10.1097/PRS.0b013e318208d2ac.
8
Infantile hemangioma.婴儿血管瘤。
Pediatr Clin North Am. 2010 Oct;57(5):1069-83. doi: 10.1016/j.pcl.2010.07.008. Epub 2010 Aug 21.
9
Infantile hemangiomas with minimal or arrested growth: a retrospective case series.生长缓慢或停止生长的婴幼儿血管瘤:一项回顾性病例系列研究
Arch Dermatol. 2010 Sep;146(9):971-6. doi: 10.1001/archdermatol.2010.197.
10
Outcomes of childhood hemangiomas treated with the pulsed-dye laser with dynamic cooling: a retrospective chart analysis.采用脉冲染料激光联合动态冷却治疗儿童血管瘤的疗效:回顾性图表分析。
Dermatol Surg. 2009 Dec;35(12):1947-54. doi: 10.1111/j.1524-4725.2009.01356.x.