Dowling J N, McDevitt D A, Pasculle A W
Antimicrob Agents Chemother. 1985 Feb;27(2):272-4. doi: 10.1128/AAC.27.2.272.
Erythromycin-resistant Legionella spp. variants were obtained by a single passage of the naturally occurring bacteria on medium containing various concentrations of erythromycin. By disk diffusion susceptibility testing, at least three different phenotypic patterns of cross-resistance to macrolide, lincosamide, and streptogramin B antibiotics were observed among the 26 erythromycin-resistant strains examined.
通过将天然存在的细菌在含有不同浓度红霉素的培养基上传代一次,获得了对红霉素耐药的嗜肺军团菌变种。通过纸片扩散法药敏试验,在所检测的26株红霉素耐药菌株中,观察到至少三种对大环内酯类、林可酰胺类和链阳菌素B抗生素的不同交叉耐药表型模式。