Pham Lan T, Le Hanh T M, Tam Le T T, Dao Hien T, Vu Minh X, Ngo Thu H A, Lu Le T, Nguyen Dung T
Institute for Tropical Technology-Vietnam Academy of Science and Technology (VAST) 18 Hoang Quoc Viet Hanoi Vietnam
Graduate University of Science and Technology, VAST 18 Hoang Quoc Viet Hanoi Vietnam.
RSC Adv. 2025 Jan 27;15(4):2792-2799. doi: 10.1039/d4ra07269c. eCollection 2025 Jan 23.
Hospital wastewater (HWW) is a major pollutant that presents significant risks to both environmental and human health. In this study, we developed a novel, inexpensive and highly antibacterial magnetic nanocomposite composed of FeO nanoparticles synthesised from spent pickling liquors, coated with chitosan and then integrated with polyhexamethylene guanidine hydrochloride (FeO@CS@PHMG) using sodium tripolyphosphate (TPP) as a crosslinking agent. The obtained results revealed that the synthesised nanocomposite exhibited high antibacterial activity against and . At a relatively low nanocomposite dosage of 2 μg mL, it effectively eliminated all at a concentration of ∼10 CFU mL within one min. For , a higher dosage of 5 μg mL and a longer time of 5 min were required for complete elimination. In real HWW treatment tests, 99.4% of and 95.8% of total coliforms were eliminated at a nanocomposite dosage of 10 μg mL. At 30 μg mL, the nanocomposite completely removed all .
医院废水（HWW）是一种主要污染物，对环境和人类健康都构成重大风险。在本研究中，我们开发了一种新型、廉价且具有高度抗菌性的磁性纳米复合材料，它由从废酸洗液中合成的FeO纳米颗粒组成，包覆壳聚糖，然后使用三聚磷酸钠（TPP）作为交联剂与聚六亚甲基胍盐酸盐（FeO@CS@PHMG）整合。所得结果表明，合成的纳米复合材料对[具体细菌名称1]和[具体细菌名称2]表现出高抗菌活性。在相对较低的纳米复合材料剂量2μg/mL时，它能在1分钟内有效消除浓度约为10⁶CFU/mL的所有[具体细菌名称1]。对于[具体细菌名称2]，完全消除需要更高的剂量5μg/mL和更长的时间5分钟。在实际医院废水处理测试中，在纳米复合材料剂量为10μg/mL时，99.4%的[具体细菌名称）]和95.8%的总大肠菌群被消除。在30μg/mL时，纳米复合材料完全去除了所有[具体细菌名称2]。
