Yu Zhonghao, Yuan Yuhao, Zhang Jiaxin, Shi Qing, Gao Hang, Zhou Yiwu
Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Huangshi Public Security Bureau, Huangshi, 435000, China.
Forensic Sci Med Pathol. 2025 Jan 29. doi: 10.1007/s12024-025-00956-2.
Mushroom poisoning incidents happen infrequently, yet owing to the non-lethal nature of most toxins and the efficacy of timely treatment, fatalities from mushroom poisoning are uncommon, leading to a scarcity of pertinent clinical and pathological data. Here, we reported a case of death caused by the consumption of raw mushrooms, alongside detailed clinical data and multi-organs pathological alterations, which underscored its potential significant reference value in forensic practice. Futhermore, ibotenic acid, a type of mushroom toxin, was detected both in the patient's blood and gastric lavage fluid about 19 h after the consumption of mushrooms, and was successfully quantified at concentrations of 0.381 µg/mL and 0.202 µg/mL, respectively, indicating a relatively significant finding.
蘑菇中毒事件并不常见，但由于大多数毒素的非致命性以及及时治疗的有效性，蘑菇中毒导致的死亡并不常见，从而导致相关临床和病理数据稀缺。在此，我们报告了一例因食用生蘑菇导致死亡的病例，并附上详细的临床数据和多器官病理改变，这凸显了其在法医实践中潜在的重要参考价值。此外，在食用蘑菇约19小时后，在患者血液和洗胃液中均检测到一种蘑菇毒素——鹅膏蕈氨酸，并分别成功定量，浓度为0.381μg/mL和0.202μg/mL，这是一个相对重要的发现。
