Yin Lingtao, Kuai Mengni, Liu Zhuo, Zou Binbin, Wu Ping
Department of Pharmacy, Loudi Hospital of Traditional Chinese Medicine, Loudi, Hunan, China.
Department of Pharmacy, Changde Hospital, Xiangya School of Medicine, Central South University (The First People's Hospital of Changde City), Changde, Hunan, China.
Front Nutr. 2025 Jan 15;11:1522555. doi: 10.3389/fnut.2024.1522555. eCollection 2024.
We aimed to assess the global impact of chronic kidney disease (CKD) attributable to dietary risk factors.
The research utilized data from the Global Burden of Disease Study 2021 to evaluate age-standardized mortality rates (ASMR), disability-adjusted life years (DALYs), and estimated annual percentage changes (EAPCs) linked to CKD resulting from dietary risk factors.
From 1990 to 2021, both the ASMR and age-standardized DALY rate (ASDR) for CKD attributable to dietary risk factors exhibited an overall increasing trend globally. The mortality EAPC was 0.65, while the EAPC for DALYs stood at 0.39. Among dietary risk factors examined, a diet high in sugar-sweetened beverages was associated with the most substantial increase in CKD burden. Notably, Central sub-Saharan Africa bore the highest burden of CKD due to dietary risk factors, with an ASMR of 10.24 and an ASDR of 229.23. The increases in ASMR and ASDR were more pronounced in high-income regions, particularly in Latin America and the Caribbean, where the EAPC values for ASMR were 1.45 and 1.05, respectively, and for ASDR were 1.08 and 0.96. Furthermore, the burden of CKD was notably higher among middle-aged and elderly individuals, especially men aged 65 and above.
The global disease burden attributed to dietary risk factors for CKD is increasing. A diet high in sugar-sweetened beverages exerted the most significant impact on CKD. There is a high incidence in Central sub-Saharan Africa, as well as in high-income regions and Latin America and the Caribbean.
我们旨在评估饮食风险因素所致慢性肾脏病（CKD）的全球影响。
本研究利用2021年全球疾病负担研究的数据，评估与饮食风险因素导致的CKD相关的年龄标准化死亡率（ASMR）、伤残调整生命年（DALYs）和估计年度百分比变化（EAPCs）。
1990年至2021年期间，全球范围内，饮食风险因素所致CKD的ASMR和年龄标准化DALY率（ASDR）总体呈上升趋势。死亡率EAPC为0.65，而DALYs的EAPC为0.39。在所研究的饮食风险因素中，高糖饮料饮食与CKD负担的增加最为显著相关。值得注意的是，撒哈拉以南非洲中部地区因饮食风险因素导致的CKD负担最高，ASMR为10.24，ASDR为229.23。高收入地区的ASMR和ASDR增长更为明显，尤其是拉丁美洲和加勒比地区，其ASMR的EAPC值分别为1.45和1.05，ASDR的EAPC值分别为1.08和0.96。此外，中年和老年人群中CKD负担明显更高，尤其是65岁及以上的男性。
饮食风险因素所致CKD的全球疾病负担正在增加。高糖饮料饮食对CKD的影响最为显著。撒哈拉以南非洲中部地区以及高收入地区、拉丁美洲和加勒比地区的发病率较高。
