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从一名脑膜炎患者中分离出库氏棘阿米巴。

Isolation of Acanthamoeba culbertsoni from a patient with meningitis.

作者信息

Lalitha M K, Anandi V, Srivastava A, Thomas K, Cherian A M, Chandi S M

出版信息

J Clin Microbiol. 1985 Apr;21(4):666-7. doi: 10.1128/jcm.21.4.666-667.1985.

DOI:10.1128/jcm.21.4.666-667.1985
PMID:3988911
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC271748/
Abstract

A case of amoebic meningitis, presumably primary, was encountered in the Christian Medical College Hospital, Vellore, South India, in November 1983. The patient, a 40-year-old man, had cerebrospinal fluid rhinorrhea before the meningitis developed. Acanthamoeba culbertsoni was repeatedly demonstrated in and cultured from the cerebrospinal fluid. The patient responded dramatically to a combination therapy of penicillin and chloramphenicol.

摘要

1983年11月,在印度南部韦洛尔的基督教医学院医院,遇到一例推测为原发性的阿米巴脑膜炎病例。患者为一名40岁男性,在脑膜炎发病前有脑脊液鼻漏。在脑脊液中反复检测到库氏棘阿米巴并从中培养出该病原体。患者对青霉素和氯霉素联合治疗反应显著。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a69/271748/36962004c51c/jcm00117-0215-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a69/271748/36962004c51c/jcm00117-0215-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a69/271748/36962004c51c/jcm00117-0215-a.jpg

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本文引用的文献

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Experimental infection of mice and monkeys by Acanthamoeba.棘阿米巴对小鼠和猴子的实验性感染。
Am J Pathol. 1959 Jan-Feb;35(1):185-97.
2
Primary amoebic meningoencephalitis: a report of two cases and antibiotic and immunologic studies.原发性阿米巴脑膜脑炎:两例报告及抗生素与免疫学研究
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Chronic amebic meningoencephalitis.慢性阿米巴脑膜脑炎
从印度的棘阿米巴脑膜炎/脑膜脑炎(AME)患者中分离和基因分型棘阿米巴属。
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Treatment of granulomatous amoebic encephalitis with voriconazole and miltefosine in an immunocompetent soldier.免疫功能正常士兵中伏立康唑联合米替福新治疗嗜中性粒细胞性脑脓肿
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Biology and pathogenesis of Acanthamoeba.棘阿米巴的生物学和发病机制。
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Acanthameba meningitis with successful outcome.棘阿米巴脑膜炎,结局良好。
Indian J Pediatr. 2009 Oct;76(10):1063-4. doi: 10.1007/s12098-009-0205-z. Epub 2009 Nov 12.
8
Successful treatment of disseminated Acanthamoeba sp. infection with miltefosine.米替福新成功治疗播散性棘阿米巴属感染
Emerg Infect Dis. 2008 Nov;14(11):1743-6. doi: 10.3201/eid1411.070854.
9
Inability to make a premortem diagnosis of Acanthamoeba species infection in a patient with fatal granulomatous amebic encephalitis.无法对患有致命性肉芽肿性阿米巴脑炎的患者进行棘阿米巴属感染的生前诊断。
J Clin Microbiol. 2005 Jun;43(6):3003-6. doi: 10.1128/JCM.43.6.3003-3006.2005.
10
Acanthamoeba spp. as agents of disease in humans.棘阿米巴属作为人类疾病的病原体。
Clin Microbiol Rev. 2003 Apr;16(2):273-307. doi: 10.1128/CMR.16.2.273-307.2003.
Arch Neurol. 1982 Jan;39(1):56-7. doi: 10.1001/archneur.1982.00510130058016.
4
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Acute pyogenic meningitis probably due to Acanthamoeba sp.: a preliminary report.急性化脓性脑膜炎可能由棘阿米巴属引起:一份初步报告。
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7
Meningoencephalitis due to pathogenic free-living amoebae. Report of two cases.致病性自由生活阿米巴引起的脑膜脑炎。两例报告。
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Re-definition of the genus Acanthamoeba with descriptions of three species.棘阿米巴属的重新定义及三种新物种的描述。
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