Suppr超能文献

巴基斯坦开伯尔-普赫图赫瓦省传染病、非传染病、残疾及相关风险因素的患病率:开伯尔-普赫图赫瓦省综合人口与健康调查(2016 - 2017年)的结果

Prevalence of communicable, non-communicable diseases, disabilities and related risk factors in Khyber Pakhtunkhwa Pakistan: Findings from the Khyber Pakhtunkhwa Integrated Population and Health Survey (2016-17).

作者信息

Haq Ziaul, Afaq Saima, Ibrahim Muhammad, Asim Muhammad

机构信息

Institute of Public Health & Social Sciences (IPH&SS), Khyber Medical University (KMU), Peshawar, Pakistan.

Institute of Health & Wellbeing, University of Glasgow, Glasgow, United Kingdom.

出版信息

PLoS One. 2025 Feb 3;20(2):e0308209. doi: 10.1371/journal.pone.0308209. eCollection 2025.

Abstract

INTRODUCTION

Pakistan is facing a triple burden of diseases: communicable diseases (CDs), non-communicable diseases (NCDs) and disabilities. There is limited evidence on the patterns of these diseases in Pakistan, specifically Khyber Pakhtunkhwa. Additionally there remains limited study on the impact of sex-, age and setting-stratified morbidities in Khyber Pakhtunkhwa.

OBJECTIVES

The objective of this study was to present the demographic characteristics and the burden of locally-specific CDs (hepatitis B and C, TB, AIDS), NCDs (diabetes, renal diseases, asthma, epilepsy, coronary heart diseases, cancer, hypertension, cholesterol, thalassemia), and disabilities (congenital, post-disease, post-injury, paralysis) stratified by sex, age and setting in the Khyber Pakhtunkhwa province of Pakistan.

MATERIAL AND METHODS

The Khyber Pakhtunkhwa Integrated Population and Health Survey (KP-IPHS) was conducted in 2016-17 to gather comprehensive information about the demographic characteristics and locale-specific health-related issues of the people of Khyber Pakhtunkhwa, Pakistan. This cross-sectional survey was conducted in 24 districts across all 7 divisions of Khyber Pakhtunkhwa on population ageing ≥18 years. A total of 20704 respondents were taken from primary (n = 1061) and secondary sampling units (n = 15724), designed with considerations for urban/rural and socio-economic status. Each primary unit included 250-300 households. The sample selection utilised a multi-staged stratified systematic cluster sampling technique, involving the inclusion of every 16th household in rural areas and every 12th household in urban areas. Observations were recorded on demographics, quality of life, physical activity, BMI, disabilities, CDs and NCDs.

RESULTS

Among all NCDs, hypertension has the highest prevalence (29.2%), showing a significant difference between females (32.7%) and males (25.0%). The proportion of males and females with diabetes is 7.4% and 5.2%, respectively, with a more substantial percentage (11.2%) observed in the ≥50 years' age group compared to 2.5% in the 18-29 years' age group and 5.0% in the 30-49 years' age group. Among the included CDs, hepatitis B and C (0.5% and 0.8%, respectively) are most prevalent. Hepatitis B is more common in females (0.8%) and in rural settings (0.6%) compared to males (0.3%) and urban settings (0.2%), respectively. The prevalence of congenital disabilities is the highest of all disabilities, with a significantly high prevalence in females (5.3%) and rural settings (3.5%) compared to males (0.9%) and urban settings (0.6%) respectively. Furthermore, post-injury, post-disease disabilities, and paralysis significantly increase with age (P < 0.001).

CONCLUSIONS

Our findings show that the prevalence of CDs, NCDs and disabilities varies across sex, age and settings, with a notable prevalence in females and the old-age population (≥50 years). The results emphasise the necessity of public health efforts, such as screening, prevention, and treatment, to tackle the triple burden of CDs, NCDs, and disabilities in Khyber Pakhtunkhwa Pakistan.

摘要

引言

巴基斯坦面临着疾病的三重负担:传染病、非传染病和残疾问题。关于这些疾病在巴基斯坦,特别是开伯尔-普赫图赫瓦省的发病模式,证据有限。此外,关于开伯尔-普赫图赫瓦省按性别、年龄和环境分层的发病率影响的研究仍然有限。

目的

本研究的目的是呈现巴基斯坦开伯尔-普赫图赫瓦省按性别、年龄和环境分层的当地特定传染病(乙型和丙型肝炎、结核病、艾滋病)、非传染病(糖尿病、肾脏疾病、哮喘、癫痫、冠心病、癌症、高血压、胆固醇、地中海贫血)和残疾(先天性、疾病后、受伤后、瘫痪)的人口特征和负担情况。

材料与方法

2016 - 2017年开展了开伯尔-普赫图赫瓦省综合人口与健康调查(KP - IPHS),以收集有关巴基斯坦开伯尔-普赫图赫瓦省人口的人口特征和当地特定健康相关问题的全面信息。这项横断面调查在开伯尔-普赫图赫瓦省所有7个分区的24个地区针对年龄≥18岁的人口进行。总共从初级(n = 1061)和二级抽样单位(n = 15724)选取了20704名受访者,抽样设计考虑了城乡和社会经济地位。每个初级单位包括250 - 300户家庭。样本选择采用多阶段分层系统整群抽样技术,农村地区每16户家庭选1户,城市地区每12户家庭选1户。记录了有关人口统计学、生活质量、身体活动、体重指数、残疾、传染病和非传染病的观察数据。

结果

在所有非传染病中,高血压患病率最高(29.2%),女性(32.7%)和男性(25.0%)之间存在显著差异。患有糖尿病的男性和女性比例分别为7.4%和5.2%,≥50岁年龄组的比例(11.2%)明显高于18 - 29岁年龄组的2.5%和30 - 49岁年龄组的5.0%。在所纳入的传染病中,乙型和丙型肝炎(分别为0.5%和0.8%)最为普遍。乙型肝炎在女性(0.8%)和农村地区(0.6%)中比男性(0.3%)和城市地区(0.2%)更为常见。先天性残疾在所有残疾中患病率最高,女性(5.3%)和农村地区(3.5%)的患病率分别显著高于男性(从0.9%)和城市地区(0.6%)。此外,受伤后、疾病后残疾和瘫痪随年龄显著增加(P < 0.001)。

结论

我们的研究结果表明,传染病、非传染病和残疾的患病率在性别、年龄和环境方面存在差异,在女性和老年人口(≥50岁)中患病率显著。结果强调了公共卫生努力的必要性,如筛查、预防和治疗,以应对巴基斯坦开伯尔-普赫图赫瓦省传染病、非传染病和残疾的三重负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bc4/11790158/ecacfe0427b4/pone.0308209.g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验