Tyler Jasper L, Trauner Dirk, Glorius Frank
University of Muenster, Institute for Organic Chemistry, Corrensstrasse 36, 48149 Muenster, Germany.
Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA.
Chem Soc Rev. 2025 Mar 31;54(7):3272-3292. doi: 10.1039/d4cs01046a.
So you've discovered a reaction. But how do you turn this new discovery into a fully-fledged program that maximises the potential of your novel transformation? Herein, we provide a student's checklist to serve as a helpful guide for synthesis development, allowing you to thoroughly investigate the chemistry in question while ensuring that no key aspect of the project is overlooked. A wide variety of the most illuminating synthetic and spectroscopic techniques will be summarised, in conjunction with literature examples and our own insights, to provide sound justifications for their implementation towards the goal of developing new reactions.
所以你发现了一种反应。但你如何将这一新发现转化为一个成熟的方案,以充分发挥你新转化反应的潜力呢?在此,我们提供一份学生清单,作为合成方法开发的有用指南,让你能够全面研究相关化学问题,同时确保项目的关键方面不被忽视。我们将结合文献实例和自身见解,总结各种最具启发性的合成和光谱技术,为其在开发新反应目标中的应用提供合理依据。