Hill Laura E, Blackmore Lorna, Narayanan Manjith, Carruthers Emma, Ferguson Richard, Gahleitner Florian, Urquhart Donald S
Department of Paediatric Respiratory & Sleep Medicine, Royal Hospital for Children and Young People, Edinburgh, United Kingdom.
Department of Child Life and Health, The University of Edinburgh, Edinburgh, United Kingdom.
J Clin Sleep Med. 2025 Jun 1;21(6):1129-1132. doi: 10.5664/jcsm.11568.
Central sleep apnea due to Cheyne-Stokes respiration is frequently described in adults with cardiac failure, but few (< 20) cases are reported in children. We report the case of a 10-year-old male with dilated cardiomyopathy and cardiac failure (left ventricular ejection fraction 36%), in whom recurrent, prolonged pauses in breathing during sleep were noted. A cardiorespiratory polygraphy sleep study was performed, which demonstrated the presence of central sleep apnea due to Cheyne-Stokes respiration. A total of 373 central events were scored and central apnea-hypopnea index was 47.4 events/h. Overnight continuous positive airways pressure was commenced via a nasal mask. Both child and mother reported improved well-being on continuous positive airways pressure, and a repeat cardiorespiratory polygraphy on continuous positive airways pressure noted a fall in central apnea-hypopnea index to 1.2 events/h. We believe this to be the first case describing successful treatment of central sleep apnea due to Cheyne-Stokes respiration in a child using continuous positive airways pressure. The improvement in patient well-being highlights the importance of a sleep history and/or sleep studies in children with cardiac failure.
Hill LE, Blackmore L, Narayanan M, et al. Diagnosis and management of Cheyne-Stokes respiration as a complication of dilated cardiomyopathy in a 10-year-old child. . 2025;21(6):1129-1132.
因潮式呼吸导致的中枢性睡眠呼吸暂停在成年心力衰竭患者中经常被描述,但儿童病例报告较少(<20例)。我们报告一例10岁男性扩张型心肌病合并心力衰竭(左心室射血分数36%)患者,其睡眠期间出现反复、长时间呼吸暂停。进行了一项多导睡眠呼吸监测睡眠研究,结果显示存在因潮式呼吸导致的中枢性睡眠呼吸暂停。共记录到373次中枢性事件,中枢性呼吸暂停低通气指数为47.4次/小时。通过鼻罩开始夜间持续气道正压通气治疗。患儿和母亲均表示持续气道正压通气治疗后舒适度有所改善,复查多导睡眠呼吸监测显示持续气道正压通气治疗后中枢性呼吸暂停低通气指数降至1.2次/小时。我们认为这是首例描述使用持续气道正压通气成功治疗儿童因潮式呼吸导致的中枢性睡眠呼吸暂停的病例。患者舒适度的改善凸显了心力衰竭患儿睡眠史和/或睡眠研究的重要性。
Hill LE, Blackmore L, Narayanan M,等。10岁儿童扩张型心肌病并发症潮式呼吸的诊断与管理。. 2025;21(6):1129 - 1132。