Di Filippo Simone, Messina Antonio, Pelosi Paolo, Robba Chiara
From the Department of Biotechnology and Sciences of Life, Anesthesia and Intensive Care, ASST Sette Laghi, University of Insubria, Varese (SDF), IRCCS Humanitas Research Hospital, Via Alessandro Manzoni, Rozzano (AM), Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan (AM), IRCCS Ospedale Policlinico San Martino (PP, CR) and Department of Surgical Sciences and Integrated Diagnostics, DISC, University of Genoa, Genoa, Italy (PP, CR).
Eur J Anaesthesiol Intensive Care. 2023 Jun 22;2(4):e0029. doi: 10.1097/EA9.0000000000000029. eCollection 2023 Aug.
Traumatic brain injury (TBI), a leading cause of death and poor neurological outcomes in trauma patients, is a primary cause of severe disability among survivors and a major public health burden globally. Optimal haemodynamic management is a keystone of care in avoiding secondary brain injury, and contributes to minimising mortality and morbidity. Although some important progress has been achieved, a paucity of high-quality recommendations still exists. The purpose of this article is to review the current knowledge on TBI-associated haemodynamic tenets, in order to summarise the most important aspects of this heterogeneous and complex field.
创伤性脑损伤(TBI)是创伤患者死亡和神经功能不良结局的主要原因,是幸存者严重残疾的主要原因,也是全球主要的公共卫生负担。优化血流动力学管理是避免继发性脑损伤的护理关键,有助于降低死亡率和发病率。尽管已取得一些重要进展,但高质量的建议仍然匮乏。本文旨在综述目前关于TBI相关血流动力学原则的知识,以总结这一异质性和复杂领域的最重要方面。