Goyal Madhav A, Agarwal Kanishka, Garg Kashika, Jheetay Himani M, Jheetay Sanket, Bhardwaj Aman
Department of Medicine, Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, Uttarakhand, India.
Department of Biochemistry, GEIMS, Dehradun, Uttarakhand, India.
J Pharm Bioallied Sci. 2024 Dec;16(Suppl 4):S3531-S3533. doi: 10.4103/jpbs.jpbs_1013_24. Epub 2024 Oct 21.
This study explores the pulmonary function of young adults living in hilly terrains at low altitudes (around 1,800 ft), assessing the impact of elevation on lung health and potential gender-based differences using digital spirometry.
Pulmonary functions, including forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), FEV1/FVC ratio, and peak expiratory flow rate, were measured in individuals aged 18-24 years. Differences between males and females were examined using independent -tests and Pearson correlation tests to analyze the relationships between various pulmonary metrics.
Males demonstrated higher mean values in FVC and FEV1 compared to females, though the FEV1/FVC ratio remained consistent across genders. Correlation analysis within the total sample and across genders revealed significant relationships among the tests.
The study highlights low altitude's physiological effects on lung function, with gender differences in pulmonary findings. These findings necessitate gender-specific approaches in health interventions and emphasize the importance of altitude consideration in respiratory health research.
本研究探讨生活在低海拔（约1800英尺）山区的年轻人的肺功能，使用数字肺活量测定法评估海拔高度对肺部健康的影响以及潜在的性别差异。
对18至24岁的个体测量肺功能，包括用力肺活量（FVC）、1秒用力呼气量（FEV1）、FEV1/FVC比值和呼气峰值流速。使用独立样本t检验和Pearson相关检验检查男性和女性之间的差异，以分析各种肺指标之间的关系。
与女性相比，男性的FVC和FEV1平均值更高，尽管FEV1/FVC比值在不同性别之间保持一致。总样本内和不同性别之间的相关分析显示各项测试之间存在显著关系。
该研究突出了低海拔对肺功能的生理影响，肺部检查结果存在性别差异。这些发现需要在健康干预中采取针对性别的方法，并强调在呼吸健康研究中考虑海拔高度的重要性。
