Tuttle S, Aggett P J, Campbell D, MacGillivray I
Am J Clin Nutr. 1985 May;41(5):1032-41. doi: 10.1093/ajcn/41.5.1032.
A longitudinal study of plasma zinc and copper concentration and plasma volume was carried out in 33 normal healthy primigravidae for comparison with 31 primigravidae selected as being at risk of delivering a growth retarded baby. Neither group received mineral or vitamin supplements. In Group A, plasma zinc concentration fell as plasma volume increased between 14 weeks and 35 weeks. Intravascular mass of zinc therefore increased and showed significant correlation with intravascular mass of albumin. Both of these were significantly lower in Group B, reflecting poorer plasma volume expansion. Plasma copper concentration mirrored the increase in plasma ceruloplasmin and was comparable in both groups. Plasma zinc and copper concentrations were unaffected by smoking or by method of feeding and there was no correlation found with percentile birth weight distribution. In both groups at 30 weeks daily dietary zinc intake was approximately half the Recommended Dietary Allowance.
对33名正常健康初产妇进行了一项关于血浆锌和铜浓度以及血浆容量的纵向研究，并与31名被选定为有分娩发育迟缓婴儿风险的初产妇进行比较。两组均未接受矿物质或维生素补充剂。在A组中，血浆锌浓度在14周和35周之间随着血浆容量的增加而下降。因此，血管内锌质量增加，并且与血管内白蛋白质量呈显著相关。这两者在B组中均显著较低，反映出较差的血浆容量扩张。血浆铜浓度反映了血浆铜蓝蛋白的增加，并且在两组中相当。血浆锌和铜浓度不受吸烟或喂养方式的影响，并且与出生体重百分位数分布没有相关性。在两组中，30周时每日膳食锌摄入量约为推荐膳食摄入量的一半。
