Nateghi Ariana, Desrochers Julie
Department of Dermatology, Sherbrooke University, Sherbrooke, Canada.
Departement of Dermatology, Charles-Le Moyne Hospital, Longueuil, Canada.
SAGE Open Med Case Rep. 2025 Feb 17;13:2050313X251320480. doi: 10.1177/2050313X251320480. eCollection 2025.
Discoid lupus erythematosus (DLE) is a chronic autoimmune condition primarily affecting the head and neck, with palmoplantar involvement (ppDLE) being an uncommon presentation. We present a case of a 46-year-old male with ppDLE and rare perineal involvement, confirmed through biopsy and serological findings, including positive RNP and Sm antibodies. This case underscores the importance of recognizing atypical presentations of DLE, which may indicate a higher risk of systemic progression and require tailored management strategies.
盘状红斑狼疮（DLE）是一种主要累及头颈部的慢性自身免疫性疾病，掌跖受累（掌跖盘状红斑狼疮，ppDLE）是一种不常见的表现形式。我们报告一例46岁男性患有掌跖盘状红斑狼疮且罕见地累及会阴，通过活检和血清学检查结果确诊，包括核糖核蛋白（RNP）抗体和史密斯（Sm）抗体阳性。该病例强调了认识盘状红斑狼疮非典型表现的重要性，这可能预示着更高的系统性进展风险，需要制定针对性的管理策略。
